| Devon | ||||
| Date | Home | H | A | Away |
| 17/05/2001 | Appledore | 5 | 2 | Exeter Civil Service |
| 17/05/2001 | Buckfastleigh Rangers | 2 | 5 | Stoke Gabriel |
| 17/05/2001 | Cullompton Rangers | 0 | 0 | Vospers Oak Villa |
| 17/05/2001 | Ivybridge Town | 1 | 3 | Elburton Villa |
| 17/05/2001 | Newton Abbot | 5 | 1 | Alphington |
| 16/05/2001 | Buckland Athletic (P) | 2 | 0 | Ottery St Mary |
| 16/05/2001 | Crediton United | 4 | 3 | Dartmouth |
| 15/05/2001 | Ivybridge Town | 3 | 3 | Topsham Town |
| 15/05/2001 | Newton Abbot | 1 | 1 | Cullompton Rangers |
| 14/05/2001 | Dartmouth | 2 | 2 | Willand Rovers |
| 14/05/2001 | Elburton Villa | 3 | 0 | Crediton United |
| 14/05/2001 | Ottery St Mary | 10 | 0 | Buckfastleigh Rangers |
| 13/05/2001 | Appledore | 2 | 4 | Elburton Villa |
| 13/05/2001 | Newton Abbot | 1 | 1 | Ivybridge Town |
| 12/05/2001 | Buckfastleigh Rangers | 0 | 2 | Ivybridge Town |
| 11/05/2001 | Crediton United | 2 | 4 | Buckland Athletic (P) |
| 11/05/2001 | Ottery St Mary | 2 | 2 | Newton Abbot Spurs |
| 09/05/2001 | Alphington | 4 | 6 | Cullompton Rangers |
| 09/05/2001 | Appledore | 3 | 0 | Topsham Town |
| 09/05/2001 | Buckland Athletic (P) | 5 | 0 | Buckfastleigh Rangers |
| 09/05/2001 | Dartmouth | 4 | 1 | Crediton United |
| 09/05/2001 | Elburton Villa | 2 | 4 | Vospers Oak Villa |
| 09/05/2001 | Ivybridge Town | 6 | 1 | Budleigh Salterton |
| 09/05/2001 | Newton Abbot | 1 | 3 | Willand Rovers |
| 09/05/2001 | Ottery St Mary | 6 | 1 | Plymstock United |
| 07/05/2001 | Buckfastleigh Rangers | 2 | 2 | Appledore |
| 07/05/2001 | Buckland Athletic (P) | 3 | 3 | Newton Abbot Spurs |
| 07/05/2001 | Budleigh Salterton | 1 | 1 | Willand Rovers |
| 07/05/2001 | Dartmouth | 2 | 2 | Ottery St Mary |
| 07/05/2001 | Heavitree United | 3 | 1 | Newton Abbot |
| 07/05/2001 | Stoke Gabriel | 2 | 2 | Cullompton Rangers |
| 07/05/2001 | Topsham Town | 0 | 1 | Alphington |
| 05/05/2001 | Appledore | 2 | 1 | Newton Abbot Spurs |
| 05/05/2001 | Buckfastleigh Rangers | 1 | 6 | Exeter Civil Service |
| 05/05/2001 | Budleigh Salterton | 2 | 0 | Crediton United |
| 05/05/2001 | Cullompton Rangers | 0 | 1 | Alphington |
| 05/05/2001 | Dartmouth | 2 | 3 | Vospers Oak Villa |
| 05/05/2001 | Ottery St Mary | 2 | 1 | Heavitree United |
| 05/05/2001 | Stoke Gabriel | 3 | 0 | Elburton Villa |
| 05/05/2001 | Topsham Town | 1 | 4 | Ivybridge Town |
| 05/05/2001 | Willand Rovers | 5 | 0 | Plymstock United |
| 03/05/2001 | Buckfastleigh Rangers | 1 | 4 | Newton Abbot |
| 03/05/2001 | Buckland Athletic (P) | 0 | 2 | Vospers Oak Villa |
| 03/05/2001 | Elburton Villa | 1 | 3 | Dartmouth |
| 03/05/2001 | Topsham Town | 0 | 4 | Ottery St Mary |
| 02/05/2001 | Budleigh Salterton | 3 | 1 | Heavitree United |
| 02/05/2001 | Stoke Gabriel | 3 | 1 | Ivybridge Town |
| 01/05/2001 | Appledore | 4 | 1 | Cullompton Rangers |
| 01/05/2001 | Buckfastleigh Rangers | 0 | 8 | Ottery St Mary |
| 01/05/2001 | Buckland Athletic (P) | 2 | 2 | Dartmouth |
| 01/05/2001 | Newton Abbot | 1 | 2 | Crediton United |
| 01/05/2001 | Topsham Town | 2 | 0 | Elburton Villa |
| 30/04/2001 | Heavitree United | 1 | 4 | Vospers Oak Villa |
| 30/04/2001 | Willand Rovers | 3 | 1 | Stoke Gabriel |
| 29/04/2001 | Elburton Villa | 4 | 2 | Budleigh Salterton |
| 28/04/2001 | Crediton United | 3 | 3 | Cullompton Rangers |
| 28/04/2001 | Dartmouth | 5 | 2 | Appledore |
| 28/04/2001 | Elburton Villa | 1 | 5 | Newton Abbot |
| 28/04/2001 | Exeter Civil Service | 2 | 1 | Plymstock United |
| 28/04/2001 | Heavitree United | 1 | 2 | Alphington |
| 28/04/2001 | Ivybridge Town | 4 | 1 | Buckfastleigh Rangers |
| 28/04/2001 | Stoke Gabriel | 1 | 1 | Newton Abbot Spurs |
| 28/04/2001 | Topsham Town | 4 | 1 | Budleigh Salterton |
| 28/04/2001 | Vospers Oak Villa | 2 | 1 | Ottery St Mary |
| 26/04/2001 | Alphington | 2 | 0 | Ivybridge Town |
| 26/04/2001 | Budleigh Salterton | 2 | 1 | Newton Abbot |
| 26/04/2001 | Exeter Civil Service | 2 | 1 | Stoke Gabriel |
| 26/04/2001 | Heavitree United | 3 | 0 | Buckfastleigh Rangers |
| 25/04/2001 | Appledore | 0 | 4 | Willand Rovers |
| 25/04/2001 | Topsham Town | 3 | 4 | Buckland Athletic (P) |
| 24/04/2001 | Alphington | 4 | 1 | Heavitree United |
| 24/04/2001 | Buckfastleigh Rangers | 1 | 4 | Dartmouth |
| 24/04/2001 | Cullompton Rangers | 1 | 3 | Budleigh Salterton |
| 24/04/2001 | Ivybridge Town | 5 | 2 | Stoke Gabriel |
| 24/04/2001 | Newton Abbot | 7 | 0 | Exeter Civil Service |
| 24/04/2001 | Newton Abbot Spurs | 1 | 1 | Ottery St Mary |
| 23/04/2001 | Crediton United | 4 | 0 | Plymstock United |
| 23/04/2001 | Elburton Villa | 2 | 0 | Buckland Athletic (P) |
| 22/04/2001 | Appledore | 2 | 1 | Ivybridge Town |
| 22/04/2001 | Ivybridge Town | 5 | 3 | Appledore |
| 21/04/2001 | Alphington | 2 | 1 | Stoke Gabriel |
| 21/04/2001 | Buckfastleigh Rangers | 2 | 0 | Elburton Villa |
| 21/04/2001 | Buckland Athletic (P) | 1 | 1 | Cullompton Rangers |
| 21/04/2001 | Crediton United | 3 | 2 | Ottery St Mary |
| 21/04/2001 | Exeter Civil Service | 1 | 0 | Dartmouth |
| 21/04/2001 | Ivybridge Town | 2 | 2 | Willand Rovers |
| 21/04/2001 | Newton Abbot | 0 | 2 | Heavitree United |
| 21/04/2001 | Newton Abbot Spurs | 1 | 1 | Budleigh Salterton |
| 21/04/2001 | Plymstock United | 4 | 4 | Topsham Town |
| 21/04/2001 | Vospers Oak Villa | 3 | 3 | Appledore |
| 18/04/2001 | Alphington | 2 | 2 | Willand Rovers |
| 18/04/2001 | Buckfastleigh Rangers | 2 | 0 | Plymstock United |
| 18/04/2001 | Buckland Athletic (P) | 1 | 0 | Exeter Civil Service |
| 18/04/2001 | Vospers Oak Villa | 1 | 2 | Elburton Villa |
| 17/04/2001 | Cullompton Rangers | 2 | 1 | Ottery St Mary |
| 16/04/2001 | Alphington | 3 | 1 | Topsham Town |
| 16/04/2001 | Cullompton Rangers | 2 | 0 | Heavitree United |
| 16/04/2001 | Dartmouth | 5 | 0 | Buckfastleigh Rangers |
| 16/04/2001 | Exeter Civil Service | 4 | 0 | Crediton United |
| 16/04/2001 | Newton Abbot | 1 | 1 | Budleigh Salterton |
| 16/04/2001 | Newton Abbot Spurs | 0 | 1 | Buckland Athletic (P) |
| 16/04/2001 | Stoke Gabriel | 1 | 1 | Willand Rovers |
| 16/04/2001 | Vospers Oak Villa | 4 | 2 | Plymstock United |
| 14/04/2001 | Appledore | 4 | 5 | Alphington |
| 14/04/2001 | Buckfastleigh Rangers | 0 | 3 | Buckland Athletic (P) |
| 14/04/2001 | Newton Abbot | 1 | 1 | Vospers Oak Villa |
| 14/04/2001 | Topsham Town | 0 | 0 | Heavitree United |
| 13/04/2001 | Budleigh Salterton | 4 | 0 | Ottery St Mary |
| 13/04/2001 | Crediton United | 1 | 0 | Appledore |
| 13/04/2001 | Ivybridge Town | 1 | 1 | Vospers Oak Villa |
| 13/04/2001 | Newton Abbot Spurs | 0 | 0 | Newton Abbot |
| 13/04/2001 | Plymstock United | 1 | 1 | Elburton Villa |
| 13/04/2001 | Stoke Gabriel | 3 | 3 | Dartmouth |
| 13/04/2001 | Willand Rovers | 2 | 0 | Cullompton Rangers |
| 12/04/2001 | Heavitree United | 5 | 2 | Exeter Civil Service |
| 11/04/2001 | Alphington | 3 | 3 | Dartmouth |
| 11/04/2001 | Ivybridge Town | 2 | 2 | Plymstock United |
| 10/04/2001 | Buckfastleigh Rangers | 1 | 0 | Vospers Oak Villa |
| 10/04/2001 | Newton Abbot | 6 | 1 | Topsham Town |
| 10/04/2001 | Ottery St Mary | 1 | 1 | Appledore |
| 09/04/2001 | Exeter Civil Service | 1 | 1 | Alphington |
| 09/04/2001 | Stoke Gabriel | 0 | 2 | Heavitree United |
| 07/04/2001 | Alphington | 5 | 0 | Plymstock United |
| 07/04/2001 | Appledore | 1 | 2 | Ottery St Mary |
| 07/04/2001 | Budleigh Salterton | 3 | 1 | Dartmouth |
| 07/04/2001 | Cullompton Rangers | 1 | 1 | Stoke Gabriel |
| 07/04/2001 | Exeter Civil Service | 1 | 3 | Buckland Athletic (P) |
| 07/04/2001 | Newton Abbot Spurs | 0 | 3 | Heavitree United |
| 07/04/2001 | Vospers Oak Villa | 6 | 3 | Buckfastleigh Rangers |
| 07/04/2001 | Willand Rovers | 2 | 1 | Crediton United |
| 04/04/2001 | Alphington | 1 | 0 | Exeter Civil Service |
| 03/04/2001 | Crediton United | 1 | 1 | Topsham Town |
| 02/04/2001 | Willand Rovers | 2 | 1 | Alphington |
| 31/03/2001 | Alphington | 3 | 1 | Vospers Oak Villa |
| 31/03/2001 | Buckland Athletic (P) | 7 | 2 | Plymstock United |
| 31/03/2001 | Crediton United | 3 | 3 | Newton Abbot |
| 31/03/2001 | Elburton Villa | 4 | 1 | Appledore |
| 31/03/2001 | Exeter Civil Service | 3 | 3 | Ivybridge Town |
| 31/03/2001 | Heavitree United | 4 | 0 | Budleigh Salterton |
| 31/03/2001 | Newton Abbot Spurs | 6 | 0 | Buckfastleigh Rangers |
| 31/03/2001 | Ottery St Mary | 2 | 5 | Dartmouth |
| 31/03/2001 | Topsham Town | 8 | 0 | Stoke Gabriel |
| 24/03/2001 | Appledore | 2 | 6 | Heavitree United |
| 24/03/2001 | Plymstock United | 2 | 7 | Newton Abbot Spurs |
| 24/03/2001 | Vospers Oak Villa | 0 | 2 | Topsham Town |
| 17/03/2001 | Dartmouth | 3 | 0 | Heavitree United |
| 17/03/2001 | Newton Abbot Spurs | 4 | 1 | Topsham Town |
| 17/03/2001 | Ottery St Mary | 2 | 1 | Crediton United |
| 17/03/2001 | Plymstock United | 1 | 6 | Buckland Athletic (P) |
| 13/03/2001 | Willand Rovers | 2 | 1 | Buckland Athletic (P) |
| 10/03/2001 | Alphington | 0 | 0 | Elburton Villa |
| 10/03/2001 | Buckland Athletic (P) | 4 | 1 | Appledore |
| 10/03/2001 | Budleigh Salterton | 2 | 0 | Buckfastleigh Rangers |
| 10/03/2001 | Crediton United | 0 | 1 | Exeter Civil Service |
| 10/03/2001 | Newton Abbot | 1 | 2 | Ottery St Mary |
| 10/03/2001 | Newton Abbot Spurs | 3 | 1 | Cullompton Rangers |
| 10/03/2001 | Topsham Town | 2 | 1 | Dartmouth |
| 07/03/2001 | Ottery St Mary | 2 | 1 | Stoke Gabriel |
| 03/03/2001 | Alphington | 1 | 5 | Ottery St Mary |
| 03/03/2001 | Appledore | 2 | 3 | Dartmouth |
| 03/03/2001 | Buckfastleigh Rangers | 1 | 2 | Heavitree United |
| 03/03/2001 | Crediton United | 2 | 2 | Willand Rovers |
| 03/03/2001 | Elburton Villa | 1 | 3 | Newton Abbot Spurs |
| 03/03/2001 | Exeter Civil Service | 1 | 2 | Budleigh Salterton |
| 03/03/2001 | Plymstock United | 1 | 6 | Cullompton Rangers |
| 27/02/2001 | Cullompton Rangers | 2 | 2 | Newton Abbot Spurs |
| 24/02/2001 | Alphington | 3 | 0 | Crediton United |
| 24/02/2001 | Cullompton Rangers | 1 | 3 | Topsham Town |
| 24/02/2001 | Dartmouth | 2 | 3 | Ivybridge Town |
| 24/02/2001 | Newton Abbot | 2 | 0 | Appledore |
| 24/02/2001 | Newton Abbot Spurs | 2 | 0 | Exeter Civil Service |
| 24/02/2001 | Ottery St Mary | 0 | 2 | Elburton Villa |
| 24/02/2001 | Stoke Gabriel | 1 | 3 | Budleigh Salterton |
| 24/02/2001 | Willand Rovers | 1 | 3 | Vospers Oak Villa |
| 21/02/2001 | Cullompton Rangers | 0 | 0 | Plymstock United |
| 17/02/2001 | Alphington | 4 | 0 | Buckfastleigh Rangers |
| 17/02/2001 | Appledore | 6 | 1 | Stoke Gabriel |
| 17/02/2001 | Cullompton Rangers | 2 | 1 | Crediton United |
| 17/02/2001 | Exeter Civil Service | 0 | 4 | Willand Rovers |
| 17/02/2001 | Heavitree United | 5 | 1 | Topsham Town |
| 17/02/2001 | Ivybridge Town | 4 | 1 | Newton Abbot Spurs |
| 17/02/2001 | Plymstock United | 2 | 4 | Newton Abbot |
| 17/02/2001 | Vospers Oak Villa | 3 | 0 | Budleigh Salterton |
| 10/02/2001 | Stoke Gabriel | 0 | 3 | Buckland Athletic (P) |
| 03/02/2001 | Alphington | 3 | 2 | Budleigh Salterton |
| 03/02/2001 | Buckland Athletic (P) | 1 | 1 | Elburton Villa |
| 03/02/2001 | Dartmouth | 3 | 1 | Cullompton Rangers |
| 03/02/2001 | Ottery St Mary | 3 | 1 | Ivybridge Town |
| 03/02/2001 | Plymstock United | 1 | 4 | Buckfastleigh Rangers |
| 03/02/2001 | Vospers Oak Villa | 0 | 2 | Newton Abbot Spurs |
| 03/02/2001 | Willand Rovers | 3 | 2 | Heavitree United |
| 27/01/2001 | Elburton Villa | 0 | 2 | Cullompton Rangers |
| 27/01/2001 | Ivybridge Town | 2 | 2 | Alphington |
| 27/01/2001 | Plymstock United | 3 | 2 | Appledore |
| 27/01/2001 | Willand Rovers | 6 | 0 | Buckfastleigh Rangers |
| 20/01/2001 | Buckfastleigh Rangers | 1 | 3 | Willand Rovers |
| 20/01/2001 | Budleigh Salterton | 1 | 2 | Elburton Villa |
| 20/01/2001 | Cullompton Rangers | 0 | 3 | Ivybridge Town |
| 20/01/2001 | Heavitree United | 6 | 2 | Crediton United |
| 20/01/2001 | Newton Abbot Spurs | 0 | 1 | Appledore |
| 20/01/2001 | Stoke Gabriel | 1 | 2 | Vospers Oak Villa |
| 20/01/2001 | Topsham Town | 2 | 2 | Exeter Civil Service |
| 13/01/2001 | Dartmouth | 2 | 2 | Budleigh Salterton |
| 13/01/2001 | Elburton Villa | 2 | 0 | Stoke Gabriel |
| 13/01/2001 | Heavitree United | 7 | 0 | Plymstock United |
| 13/01/2001 | Ivybridge Town | 3 | 2 | Buckland Athletic (P) |
| 13/01/2001 | Newton Abbot Spurs | 0 | 1 | Willand Rovers |
| 13/01/2001 | Ottery St Mary | 0 | 3 | Alphington |
| 13/01/2001 | Topsham Town | 2 | 3 | Cullompton Rangers |
| 13/01/2001 | Vospers Oak Villa | 3 | 2 | Exeter Civil Service |
| 06/01/2001 | Buckland Athletic (P) | 3 | 2 | Heavitree United |
| 06/01/2001 | Budleigh Salterton | 1 | 1 | Appledore |
| 06/01/2001 | Exeter Civil Service | 3 | 5 | Newton Abbot |
| 06/01/2001 | Newton Abbot Spurs | 1 | 0 | Alphington |
| 06/01/2001 | Plymstock United | 2 | 3 | Ottery St Mary |
| 06/01/2001 | Stoke Gabriel | 1 | 4 | Topsham Town |
| 06/01/2001 | Willand Rovers | 2 | 2 | Elburton Villa |
| 30/12/2000 | Appledore | 4 | 4 | Crediton United |
| 30/12/2000 | Budleigh Salterton | 1 | 0 | Exeter Civil Service |
| 30/12/2000 | Plymstock United | 0 | 3 | Dartmouth |
| 26/12/2000 | Cullompton Rangers | 1 | 2 | Willand Rovers |
| 26/12/2000 | Dartmouth | 4 | 1 | Stoke Gabriel |
| 26/12/2000 | Elburton Villa | 2 | 2 | Plymstock United |
| 26/12/2000 | Exeter Civil Service | 1 | 1 | Heavitree United |
| 26/12/2000 | Newton Abbot | 2 | 2 | Newton Abbot Spurs |
| 26/12/2000 | Ottery St Mary | 5 | 2 | Budleigh Salterton |
| 26/12/2000 | Vospers Oak Villa | 4 | 1 | Ivybridge Town |
| 23/12/2000 | Dartmouth | 4 | 1 | Newton Abbot |
| 23/12/2000 | Ottery St Mary | 0 | 2 | Willand Rovers |
| 23/12/2000 | Plymstock United | 1 | 2 | Budleigh Salterton |
| 23/12/2000 | Topsham Town | 0 | 2 | Vospers Oak Villa |
| 16/12/2000 | Budleigh Salterton | 0 | 2 | Buckland Athletic (P) |
| 16/12/2000 | Exeter Civil Service | 2 | 2 | Cullompton Rangers |
| 16/12/2000 | Ivybridge Town | 0 | 0 | Heavitree United |
| 16/12/2000 | Newton Abbot Spurs | 3 | 1 | Plymstock United |
| 16/12/2000 | Stoke Gabriel | 1 | 3 | Alphington |
| 16/12/2000 | Willand Rovers | 2 | 2 | Dartmouth |
| 09/12/2000 | Heavitree United | 4 | 1 | Appledore |
| 09/12/2000 | Ivybridge Town | 3 | 0 | Crediton United |
| 09/12/2000 | Vospers Oak Villa | 4 | 2 | Stoke Gabriel |
| 09/12/2000 | Willand Rovers | 2 | 1 | Newton Abbot Spurs |
| 02/12/2000 | Buckfastleigh Rangers | 3 | 1 | Topsham Town |
| 02/12/2000 | Budleigh Salterton | 1 | 1 | Vospers Oak Villa |
| 02/12/2000 | Crediton United | 2 | 3 | Elburton Villa |
| 02/12/2000 | Dartmouth | 3 | 3 | Newton Abbot Spurs |
| 02/12/2000 | Plymstock United | 0 | 2 | Willand Rovers |
| 25/11/2000 | Vospers Oak Villa | 6 | 0 | Crediton United |
| 18/11/2000 | Exeter Civil Service | 0 | 2 | Elburton Villa |
| 18/11/2000 | Heavitree United | 1 | 5 | Buckland Athletic (P) |
| 18/11/2000 | Ivybridge Town | 1 | 2 | Newton Abbot |
| 18/11/2000 | Newton Abbot Spurs | 6 | 1 | Crediton United |
| 18/11/2000 | Plymstock United | 1 | 1 | Stoke Gabriel |
| 18/11/2000 | Vospers Oak Villa | 1 | 4 | Dartmouth |
| 08/11/2000 | Newton Abbot | 0 | 0 | Buckfastleigh Rangers |
| 07/11/2000 | Willand Rovers | 8 | 0 | Topsham Town |
| 04/11/2000 | Buckland Athletic (P) | 4 | 4 | Alphington |
| 04/11/2000 | Crediton United | 0 | 3 | Budleigh Salterton |
| 04/11/2000 | Cullompton Rangers | 3 | 2 | Elburton Villa |
| 04/11/2000 | Exeter Civil Service | 3 | 4 | Topsham Town |
| 04/11/2000 | Heavitree United | 5 | 3 | Willand Rovers |
| 04/11/2000 | Newton Abbot | 3 | 2 | Plymstock United |
| 25/10/2000 | Newton Abbot | 2 | 0 | Buckland Athletic (P) |
| 23/10/2000 | Crediton United | 1 | 2 | Heavitree United |
| 21/10/2000 | Appledore | 0 | 1 | Buckland Athletic (P) |
| 21/10/2000 | Budleigh Salterton | 3 | 3 | Alphington |
| 21/10/2000 | Elburton Villa | 0 | 1 | Ottery St Mary |
| 21/10/2000 | Heavitree United | 2 | 1 | Dartmouth |
| 21/10/2000 | Ivybridge Town | 1 | 1 | Cullompton Rangers |
| 21/10/2000 | Plymstock United | 3 | 3 | Exeter Civil Service |
| 21/10/2000 | Stoke Gabriel | 2 | 3 | Crediton United |
| 21/10/2000 | Topsham Town | 3 | 1 | Buckfastleigh Rangers |
| 21/10/2000 | Vospers Oak Villa | 2 | 0 | Newton Abbot |
| 18/10/2000 | Newton Abbot | 2 | 1 | Dartmouth |
| 17/10/2000 | Willand Rovers | 5 | 2 | Exeter Civil Service |
| 14/10/2000 | Alphington | 4 | 1 | Appledore |
| 14/10/2000 | Buckland Athletic (P) | 4 | 2 | Budleigh Salterton |
| 14/10/2000 | Crediton United | 2 | 3 | Buckfastleigh Rangers |
| 14/10/2000 | Elburton Villa | 2 | 6 | Heavitree United |
| 14/10/2000 | Ottery St Mary | 0 | 1 | Vospers Oak Villa |
| 14/10/2000 | Stoke Gabriel | 0 | 5 | Newton Abbot |
| 04/10/2000 | Ottery St Mary | 4 | 1 | Topsham Town |
| 03/10/2000 | Cullompton Rangers | 0 | 2 | Buckland Athletic (P) |
| 30/09/2000 | Alphington | 1 | 1 | Newton Abbot Spurs |
| 30/09/2000 | Appledore | 4 | 1 | Budleigh Salterton |
| 30/09/2000 | Buckland Athletic (P) | 2 | 3 | Stoke Gabriel |
| 30/09/2000 | Elburton Villa | 0 | 4 | Willand Rovers |
| 30/09/2000 | Exeter Civil Service | 1 | 2 | Buckfastleigh Rangers |
| 30/09/2000 | Ivybridge Town | 5 | 0 | Ottery St Mary |
| 30/09/2000 | Plymstock United | 3 | 1 | Crediton United |
| 30/09/2000 | Vospers Oak Villa | 0 | 1 | Cullompton Rangers |
| 26/09/2000 | Newton Abbot | 1 | 4 | Stoke Gabriel |
| 25/09/2000 | Crediton United | 1 | 1 | Newton Abbot Spurs |
| 23/09/2000 | Appledore | 4 | 0 | Buckfastleigh Rangers |
| 23/09/2000 | Budleigh Salterton | 2 | 0 | Stoke Gabriel |
| 23/09/2000 | Dartmouth | 5 | 1 | Topsham Town |
| 23/09/2000 | Heavitree United | 0 | 0 | Ottery St Mary |
| 23/09/2000 | Ivybridge Town | 2 | 1 | Exeter Civil Service |
| 23/09/2000 | Newton Abbot | 11 | 0 | Elburton Villa |
| 23/09/2000 | Newton Abbot Spurs | 3 | 2 | Vospers Oak Villa |
| 23/09/2000 | Plymstock United | 2 | 2 | Alphington |
| 20/09/2000 | Ottery St Mary | 0 | 2 | Buckland Athletic (P) |
| 19/09/2000 | Willand Rovers | 2 | 0 | Appledore |
| 16/09/2000 | Buckfastleigh Rangers | 2 | 0 | Cullompton Rangers |
| 16/09/2000 | Dartmouth | 4 | 0 | Elburton Villa |
| 16/09/2000 | Exeter Civil Service | 0 | 1 | Newton Abbot Spurs |
| 16/09/2000 | Heavitree United | 1 | 0 | Ivybridge Town |
| 16/09/2000 | Stoke Gabriel | 4 | 0 | Plymstock United |
| 16/09/2000 | Topsham Town | 1 | 2 | Newton Abbot |
| 16/09/2000 | Vospers Oak Villa | 2 | 2 | Willand Rovers |
| 12/09/2000 | Cullompton Rangers | 0 | 0 | Appledore |
| 11/09/2000 | Crediton United | 1 | 5 | Alphington |
| 09/09/2000 | Alphington | 0 | 5 | Newton Abbot |
| 09/09/2000 | Appledore | 1 | 3 | Vospers Oak Villa |
| 09/09/2000 | Buckland Athletic (P) | 4 | 1 | Topsham Town |
| 09/09/2000 | Crediton United | 3 | 2 | Stoke Gabriel |
| 09/09/2000 | Cullompton Rangers | 1 | 1 | Buckfastleigh Rangers |
| 09/09/2000 | Ivybridge Town | 1 | 4 | Dartmouth |
| 09/09/2000 | Newton Abbot Spurs | 7 | 2 | Elburton Villa |
| 09/09/2000 | Ottery St Mary | 1 | 0 | Exeter Civil Service |
| 09/09/2000 | Plymstock United | 1 | 2 | Heavitree United |
| 09/09/2000 | Willand Rovers | 1 | 3 | Budleigh Salterton |
| 06/09/2000 | Alphington | 2 | 1 | Buckland Athletic (P) |
| 02/09/2000 | Buckfastleigh Rangers | 2 | 3 | Crediton United |
| 02/09/2000 | Budleigh Salterton | 3 | 1 | Ivybridge Town |
| 02/09/2000 | Dartmouth | 1 | 1 | Exeter Civil Service |
| 02/09/2000 | Elburton Villa | 1 | 0 | Alphington |
| 02/09/2000 | Heavitree United | 5 | 3 | Newton Abbot Spurs |
| 02/09/2000 | Ottery St Mary | 1 | 0 | Cullompton Rangers |
| 02/09/2000 | Stoke Gabriel | 1 | 2 | Appledore |
| 02/09/2000 | Topsham Town | 2 | 2 | Plymstock United |
| 02/09/2000 | Vospers Oak Villa | 0 | 4 | Buckland Athletic (P) |
| 02/09/2000 | Willand Rovers | 2 | 0 | Newton Abbot |
| 30/08/2000 | Plymstock United | 1 | 0 | Ivybridge Town |
| 29/08/2000 | Topsham Town | 1 | 3 | Willand Rovers |
| 28/08/2000 | Buckland Athletic (P) | 4 | 3 | Newton Abbot |
| 28/08/2000 | Exeter Civil Service | 2 | 1 | Vospers Oak Villa |
| 28/08/2000 | Newton Abbot Spurs | 0 | 3 | Stoke Gabriel |
| 26/08/2000 | Buckfastleigh Rangers | 1 | 4 | Newton Abbot Spurs |
| 26/08/2000 | Buckland Athletic (P) | 1 | 2 | Willand Rovers |
| 26/08/2000 | Budleigh Salterton | 5 | 0 | Plymstock United |
| 26/08/2000 | Crediton United | 5 | 0 | Ivybridge Town |
| 26/08/2000 | Cullompton Rangers | 1 | 5 | Newton Abbot |
| 26/08/2000 | Dartmouth | 0 | 0 | Alphington |
| 26/08/2000 | Elburton Villa | 1 | 1 | Exeter Civil Service |
| 26/08/2000 | Stoke Gabriel | 1 | 3 | Ottery St Mary |
| 26/08/2000 | Topsham Town | 1 | 2 | Appledore |
| 26/08/2000 | Vospers Oak Villa | 5 | 3 | Heavitree United |
| 23/08/2000 | Budleigh Salterton | 2 | 0 | Topsham Town |
| 23/08/2000 | Dartmouth | 6 | 2 | Buckland Athletic (P) |
| 23/08/2000 | Exeter Civil Service | 3 | 2 | Appledore |
| 23/08/2000 | Plymstock United | 0 | 3 | Vospers Oak Villa |
| 22/08/2000 | Elburton Villa | 0 | 1 | Buckfastleigh Rangers |
| 22/08/2000 | Heavitree United | 4 | 1 | Cullompton Rangers |
| 21/08/2000 | Newton Abbot Spurs | 4 | 1 | Ivybridge Town |
| 19/08/2000 | Appledore | 0 | 1 | Plymstock United |
| 19/08/2000 | Buckfastleigh Rangers | 0 | 4 | Budleigh Salterton |
| 19/08/2000 | Buckland Athletic (P) | 8 | 0 | Crediton United |
| 19/08/2000 | Cullompton Rangers | 0 | 3 | Dartmouth |
| 19/08/2000 | Heavitree United | 2 | 2 | Elburton Villa |
| 19/08/2000 | Ottery St Mary | 2 | 1 | Newton Abbot |
| 19/08/2000 | Stoke Gabriel | 1 | 1 | Exeter Civil Service |
| 19/08/2000 | Topsham Town | 1 | 9 | Newton Abbot Spurs |
| 19/08/2000 | Vospers Oak Villa | 0 | 4 | Alphington |
| 19/08/2000 | Willand Rovers | 2 | 0 | Ivybridge Town |
| 16/08/2000 | Budleigh Salterton | 0 | 0 | Cullompton Rangers |
| 16/08/2000 | Exeter Civil Service | 1 | 3 | Ottery St Mary |
| 16/08/2000 | Stoke Gabriel | 2 | 2 | Buckfastleigh Rangers |
| 15/08/2000 | Elburton Villa | 1 | 1 | Ivybridge Town |
| 15/08/2000 | Topsham Town | 2 | 0 | Crediton United |
| 14/08/2000 | Newton Abbot Spurs | 1 | 1 | Dartmouth |
| 12/08/2000 | Appledore | 2 | 1 | Newton Abbot |
| 12/08/2000 | Buckfastleigh Rangers | 0 | 2 | Alphington |
| 12/08/2000 | Buckland Athletic (P) | 5 | 0 | Ivybridge Town |
| 12/08/2000 | Budleigh Salterton | 2 | 0 | Newton Abbot Spurs |
| 12/08/2000 | Crediton United | 3 | 0 | Vospers Oak Villa |
| 12/08/2000 | Cullompton Rangers | 2 | 0 | Exeter Civil Service |
| 12/08/2000 | Dartmouth | 4 | 2 | Plymstock United |
| 12/08/2000 | Elburton Villa | 4 | 2 | Topsham Town |
| 12/08/2000 | Heavitree United | 2 | 0 | Stoke Gabriel |
| 12/08/2000 | Willand Rovers | 2 | 0 | Ottery St Mary |