| Division One | ||||
| Date | Home | H | A | Away |
| 06/05/2001 | Bolton Wanderers | 1 | 1 | Sheffield United |
| 06/05/2001 | Burnley (P) | 2 | 0 | Watford (R) |
| 06/05/2001 | Gillingham (P) | 1 | 1 | Blackburn Rovers |
| 06/05/2001 | Grimsby Town | 1 | 0 | Fulham |
| 06/05/2001 | Huddersfield Town | 1 | 2 | Birmingham City |
| 06/05/2001 | Portsmouth | 3 | 0 | Barnsley |
| 06/05/2001 | Preston North End (P) | 2 | 1 | West Bromwich Albion |
| 06/05/2001 | Sheffield Wednesday (R) | 0 | 0 | Crewe Alexandra |
| 06/05/2001 | Stockport County | 0 | 1 | Crystal Palace |
| 06/05/2001 | Tranmere Rovers | 2 | 2 | Nottingham Forest |
| 06/05/2001 | Wimbledon (R) | 0 | 0 | Norwich City |
| 06/05/2001 | Wolverhampton Wanderers | 1 | 1 | Queens Park Rangers |
| 02/05/2001 | Portsmouth | 2 | 4 | Crystal Palace |
| 02/05/2001 | Preston North End (P) | 0 | 1 | Blackburn Rovers |
| 01/05/2001 | Gillingham (P) | 0 | 3 | Watford (R) |
| 01/05/2001 | Wimbledon (R) | 1 | 1 | Huddersfield Town |
| 01/05/2001 | Wolverhampton Wanderers | 0 | 2 | Bolton Wanderers |
| 29/04/2001 | Blackburn Rovers | 3 | 1 | Portsmouth |
| 28/04/2001 | Barnsley | 0 | 1 | Bolton Wanderers |
| 28/04/2001 | Birmingham City | 1 | 0 | Grimsby Town |
| 28/04/2001 | Crewe Alexandra | 1 | 3 | Preston North End (P) |
| 28/04/2001 | Crystal Palace | 0 | 2 | Wolverhampton Wanderers |
| 28/04/2001 | Fulham | 1 | 1 | Wimbledon (R) |
| 28/04/2001 | Norwich City | 1 | 0 | Sheffield Wednesday (R) |
| 28/04/2001 | Nottingham Forest | 0 | 1 | Gillingham (P) |
| 28/04/2001 | Queens Park Rangers | 0 | 3 | Stockport County |
| 28/04/2001 | Sheffield United | 2 | 0 | Burnley (P) |
| 28/04/2001 | Watford (R) | 1 | 1 | Tranmere Rovers |
| 28/04/2001 | West Bromwich Albion | 1 | 1 | Huddersfield Town |
| 24/04/2001 | Burnley (P) | 2 | 1 | Tranmere Rovers |
| 24/04/2001 | Fulham | 2 | 0 | Wolverhampton Wanderers |
| 24/04/2001 | Grimsby Town | 1 | 4 | Blackburn Rovers |
| 24/04/2001 | Wimbledon (R) | 3 | 3 | Crewe Alexandra |
| 22/04/2001 | Preston North End (P) | 3 | 2 | Watford (R) |
| 21/04/2001 | Bolton Wanderers | 1 | 0 | Norwich City |
| 21/04/2001 | Burnley (P) | 0 | 0 | Birmingham City |
| 21/04/2001 | Gillingham (P) | 1 | 2 | West Bromwich Albion |
| 21/04/2001 | Grimsby Town | 0 | 1 | Sheffield United |
| 21/04/2001 | Huddersfield Town | 2 | 1 | Queens Park Rangers |
| 21/04/2001 | Portsmouth | 1 | 1 | Fulham |
| 21/04/2001 | Sheffield Wednesday (R) | 2 | 1 | Barnsley |
| 21/04/2001 | Stockport County | 3 | 0 | Crewe Alexandra |
| 21/04/2001 | Tranmere Rovers | 1 | 1 | Crystal Palace |
| 21/04/2001 | Wimbledon (R) | 2 | 1 | Nottingham Forest |
| 21/04/2001 | Wolverhampton Wanderers | 0 | 0 | Blackburn Rovers |
| 18/04/2001 | Crewe Alexandra | 2 | 1 | Bolton Wanderers |
| 17/04/2001 | Sheffield United | 0 | 1 | Wimbledon (R) |
| 17/04/2001 | Watford (R) | 3 | 2 | Wolverhampton Wanderers |
| 16/04/2001 | Barnsley | 0 | 4 | Preston North End (P) |
| 16/04/2001 | Birmingham City | 0 | 0 | Portsmouth |
| 16/04/2001 | Blackburn Rovers | 2 | 0 | Huddersfield Town |
| 16/04/2001 | Crewe Alexandra | 2 | 1 | Gillingham (P) |
| 16/04/2001 | Crystal Palace | 0 | 2 | Bolton Wanderers |
| 16/04/2001 | Fulham | 1 | 1 | Sheffield Wednesday (R) |
| 16/04/2001 | Norwich City | 2 | 3 | Burnley (P) |
| 16/04/2001 | Nottingham Forest | 1 | 0 | Stockport County |
| 16/04/2001 | Queens Park Rangers | 2 | 0 | Tranmere Rovers |
| 16/04/2001 | West Bromwich Albion | 0 | 1 | Grimsby Town |
| 14/04/2001 | Burnley (P) | 1 | 1 | West Bromwich Albion |
| 14/04/2001 | Gillingham (P) | 4 | 1 | Sheffield United |
| 14/04/2001 | Grimsby Town | 2 | 1 | Watford (R) |
| 14/04/2001 | Huddersfield Town | 1 | 2 | Fulham |
| 14/04/2001 | Portsmouth | 1 | 1 | Queens Park Rangers |
| 14/04/2001 | Preston North End (P) | 1 | 1 | Nottingham Forest |
| 14/04/2001 | Sheffield Wednesday (R) | 4 | 1 | Crystal Palace |
| 14/04/2001 | Stockport County | 0 | 0 | Blackburn Rovers |
| 14/04/2001 | Tranmere Rovers | 0 | 1 | Norwich City |
| 14/04/2001 | Wimbledon (R) | 1 | 1 | Barnsley |
| 14/04/2001 | Wolverhampton Wanderers | 0 | 0 | Crewe Alexandra |
| 13/04/2001 | Bolton Wanderers | 2 | 2 | Birmingham City |
| 11/04/2001 | Blackburn Rovers | 1 | 2 | Fulham |
| 10/04/2001 | Crewe Alexandra | 2 | 2 | Queens Park Rangers |
| 10/04/2001 | Preston North End (P) | 0 | 0 | Huddersfield Town |
| 10/04/2001 | Sheffield United | 1 | 1 | Norwich City |
| 10/04/2001 | Tranmere Rovers | 1 | 0 | Birmingham City |
| 10/04/2001 | Wimbledon (R) | 0 | 2 | Burnley (P) |
| 07/04/2001 | Fulham | 0 | 0 | West Bromwich Albion |
| 07/04/2001 | Gillingham (P) | 4 | 3 | Norwich City |
| 07/04/2001 | Grimsby Town | 3 | 1 | Tranmere Rovers |
| 07/04/2001 | Portsmouth | 0 | 2 | Nottingham Forest |
| 07/04/2001 | Queens Park Rangers | 1 | 3 | Blackburn Rovers |
| 07/04/2001 | Sheffield United | 1 | 2 | Barnsley |
| 07/04/2001 | Stockport County | 2 | 1 | Sheffield Wednesday (R) |
| 07/04/2001 | Watford (R) | 2 | 2 | Crystal Palace |
| 07/04/2001 | Wimbledon (R) | 3 | 1 | Birmingham City |
| 07/04/2001 | Wolverhampton Wanderers | 0 | 1 | Huddersfield Town |
| 06/04/2001 | Burnley (P) | 3 | 0 | Preston North End (P) |
| 04/04/2001 | Blackburn Rovers | 1 | 1 | Sheffield United |
| 04/04/2001 | Wolverhampton Wanderers | 0 | 1 | Wimbledon (R) |
| 03/04/2001 | Bolton Wanderers | 1 | 1 | Stockport County |
| 03/04/2001 | Crystal Palace | 0 | 0 | Huddersfield Town |
| 03/04/2001 | Watford (R) | 3 | 0 | Nottingham Forest |
| 01/04/2001 | Birmingham City | 0 | 1 | Wolverhampton Wanderers |
| 01/04/2001 | Blackburn Rovers | 5 | 0 | Burnley (P) |
| 01/04/2001 | Sheffield Wednesday (R) | 1 | 2 | Sheffield United |
| 31/03/2001 | Barnsley | 0 | 2 | Stockport County |
| 31/03/2001 | Bolton Wanderers | 2 | 2 | Wimbledon (R) |
| 31/03/2001 | Crystal Palace | 1 | 0 | Crewe Alexandra |
| 31/03/2001 | Huddersfield Town | 4 | 1 | Portsmouth |
| 31/03/2001 | Norwich City | 2 | 1 | Grimsby Town |
| 31/03/2001 | Nottingham Forest | 1 | 1 | Queens Park Rangers |
| 31/03/2001 | Preston North End (P) | 0 | 0 | Gillingham (P) |
| 31/03/2001 | West Bromwich Albion | 3 | 0 | Watford (R) |
| 30/03/2001 | Tranmere Rovers | 1 | 4 | Fulham |
| 25/03/2001 | Barnsley | 3 | 1 | Gillingham (P) |
| 25/03/2001 | West Bromwich Albion | 2 | 1 | Tranmere Rovers |
| 24/03/2001 | Birmingham City | 1 | 2 | Sheffield Wednesday (R) |
| 24/03/2001 | Burnley (P) | 2 | 1 | Queens Park Rangers |
| 20/03/2001 | Gillingham (P) | 2 | 1 | Tranmere Rovers |
| 20/03/2001 | Grimsby Town | 1 | 1 | Birmingham City |
| 18/03/2001 | Wolverhampton Wanderers | 3 | 1 | West Bromwich Albion |
| 17/03/2001 | Blackburn Rovers | 1 | 1 | Wimbledon (R) |
| 17/03/2001 | Crewe Alexandra | 1 | 0 | Portsmouth |
| 17/03/2001 | Crystal Palace | 0 | 2 | Fulham |
| 17/03/2001 | Huddersfield Town | 2 | 1 | Sheffield United |
| 17/03/2001 | Norwich City | 1 | 2 | Preston North End (P) |
| 17/03/2001 | Nottingham Forest | 0 | 2 | Bolton Wanderers |
| 17/03/2001 | Queens Park Rangers | 0 | 1 | Grimsby Town |
| 17/03/2001 | Sheffield Wednesday (R) | 2 | 0 | Burnley (P) |
| 17/03/2001 | Stockport County | 2 | 0 | Birmingham City |
| 17/03/2001 | Tranmere Rovers | 2 | 3 | Barnsley |
| 14/03/2001 | Birmingham City | 0 | 2 | Blackburn Rovers |
| 14/03/2001 | Preston North End (P) | 2 | 0 | Wolverhampton Wanderers |
| 14/03/2001 | Tranmere Rovers | 1 | 1 | Portsmouth |
| 13/03/2001 | Crewe Alexandra | 1 | 0 | Nottingham Forest |
| 13/03/2001 | Grimsby Town | 1 | 1 | Wimbledon (R) |
| 13/03/2001 | Watford (R) | 0 | 1 | Burnley (P) |
| 10/03/2001 | Barnsley | 3 | 1 | Huddersfield Town |
| 10/03/2001 | Birmingham City | 2 | 0 | Crewe Alexandra |
| 10/03/2001 | Bolton Wanderers | 3 | 3 | Gillingham (P) |
| 10/03/2001 | Fulham | 2 | 0 | Queens Park Rangers |
| 10/03/2001 | Grimsby Town | 0 | 2 | Wolverhampton Wanderers |
| 10/03/2001 | Portsmouth | 2 | 1 | Stockport County |
| 10/03/2001 | Sheffield United | 1 | 3 | Nottingham Forest |
| 10/03/2001 | Watford (R) | 4 | 1 | Norwich City |
| 10/03/2001 | West Bromwich Albion | 1 | 2 | Sheffield Wednesday (R) |
| 10/03/2001 | Wimbledon (R) | 1 | 0 | Crystal Palace |
| 07/03/2001 | Nottingham Forest | 1 | 0 | Barnsley |
| 07/03/2001 | Queens Park Rangers | 1 | 1 | Watford (R) |
| 07/03/2001 | Sheffield Wednesday (R) | 0 | 0 | Portsmouth |
| 06/03/2001 | Crewe Alexandra | 1 | 0 | Sheffield United |
| 06/03/2001 | Crystal Palace | 1 | 2 | Birmingham City |
| 06/03/2001 | Gillingham (P) | 0 | 0 | Wimbledon (R) |
| 06/03/2001 | Huddersfield Town | 0 | 0 | Grimsby Town |
| 06/03/2001 | Norwich City | 0 | 1 | West Bromwich Albion |
| 06/03/2001 | Stockport County | 0 | 0 | Burnley (P) |
| 06/03/2001 | Tranmere Rovers | 1 | 1 | Preston North End (P) |
| 04/03/2001 | Fulham | 1 | 1 | Bolton Wanderers |
| 03/03/2001 | Blackburn Rovers | 1 | 0 | West Bromwich Albion |
| 03/03/2001 | Crewe Alexandra | 3 | 1 | Tranmere Rovers |
| 03/03/2001 | Crystal Palace | 0 | 2 | Preston North End (P) |
| 03/03/2001 | Grimsby Town | 0 | 2 | Barnsley |
| 03/03/2001 | Huddersfield Town | 2 | 0 | Norwich City |
| 03/03/2001 | Portsmouth | 2 | 0 | Burnley (P) |
| 03/03/2001 | Queens Park Rangers | 1 | 3 | Sheffield United |
| 03/03/2001 | Sheffield Wednesday (R) | 2 | 1 | Gillingham (P) |
| 03/03/2001 | Stockport County | 2 | 2 | Wimbledon (R) |
| 03/03/2001 | Wolverhampton Wanderers | 2 | 0 | Nottingham Forest |
| 02/03/2001 | Birmingham City | 2 | 0 | Watford (R) |
| 27/02/2001 | Tranmere Rovers | 2 | 0 | Huddersfield Town |
| 24/02/2001 | Barnsley | 3 | 0 | Crewe Alexandra |
| 24/02/2001 | Burnley (P) | 1 | 0 | Huddersfield Town |
| 24/02/2001 | Gillingham (P) | 0 | 2 | Fulham |
| 24/02/2001 | Norwich City | 1 | 0 | Wolverhampton Wanderers |
| 24/02/2001 | Nottingham Forest | 3 | 1 | Grimsby Town |
| 24/02/2001 | Preston North End (P) | 2 | 0 | Sheffield Wednesday (R) |
| 24/02/2001 | Sheffield United | 1 | 0 | Crystal Palace |
| 24/02/2001 | Watford (R) | 2 | 2 | Stockport County |
| 24/02/2001 | West Bromwich Albion | 2 | 0 | Portsmouth |
| 24/02/2001 | Wimbledon (R) | 5 | 0 | Queens Park Rangers |
| 23/02/2001 | Bolton Wanderers | 1 | 4 | Blackburn Rovers |
| 21/02/2001 | Nottingham Forest | 0 | 1 | Sheffield Wednesday (R) |
| 20/02/2001 | Barnsley | 1 | 0 | Crystal Palace |
| 20/02/2001 | Bolton Wanderers | 2 | 2 | Grimsby Town |
| 20/02/2001 | Burnley (P) | 2 | 1 | Fulham |
| 20/02/2001 | Gillingham (P) | 0 | 1 | Queens Park Rangers |
| 20/02/2001 | Norwich City | 4 | 0 | Stockport County |
| 20/02/2001 | Preston North End (P) | 0 | 2 | Birmingham City |
| 20/02/2001 | Sheffield United | 1 | 0 | Wolverhampton Wanderers |
| 20/02/2001 | Watford (R) | 0 | 1 | Blackburn Rovers |
| 20/02/2001 | West Bromwich Albion | 2 | 2 | Crewe Alexandra |
| 17/02/2001 | Birmingham City | 2 | 1 | West Bromwich Albion |
| 17/02/2001 | Crewe Alexandra | 2 | 0 | Watford (R) |
| 17/02/2001 | Crystal Palace | 1 | 1 | Norwich City |
| 17/02/2001 | Fulham | 1 | 0 | Nottingham Forest |
| 17/02/2001 | Grimsby Town | 1 | 0 | Burnley (P) |
| 17/02/2001 | Huddersfield Town | 2 | 3 | Gillingham (P) |
| 17/02/2001 | Queens Park Rangers | 2 | 0 | Barnsley |
| 13/02/2001 | Portsmouth | 1 | 2 | Bolton Wanderers |
| 13/02/2001 | Sheffield Wednesday (R) | 1 | 0 | Tranmere Rovers |
| 13/02/2001 | Stockport County | 0 | 1 | Preston North End (P) |
| 10/02/2001 | Barnsley | 0 | 0 | Fulham |
| 10/02/2001 | Bolton Wanderers | 2 | 2 | Huddersfield Town |
| 10/02/2001 | Burnley (P) | 1 | 2 | Crystal Palace |
| 10/02/2001 | Gillingham (P) | 1 | 0 | Grimsby Town |
| 10/02/2001 | Norwich City | 1 | 1 | Crewe Alexandra |
| 10/02/2001 | Nottingham Forest | 2 | 1 | Blackburn Rovers |
| 10/02/2001 | Preston North End (P) | 5 | 0 | Queens Park Rangers |
| 10/02/2001 | Sheffield United | 3 | 1 | Birmingham City |
| 10/02/2001 | Tranmere Rovers | 0 | 2 | Wolverhampton Wanderers |
| 10/02/2001 | Watford (R) | 2 | 2 | Portsmouth |
| 10/02/2001 | West Bromwich Albion | 1 | 1 | Stockport County |
| 10/02/2001 | Wimbledon (R) | 4 | 1 | Sheffield Wednesday (R) |
| 04/02/2001 | Fulham | 1 | 1 | Sheffield United |
| 03/02/2001 | Birmingham City | 2 | 1 | Norwich City |
| 03/02/2001 | Blackburn Rovers | 0 | 0 | Barnsley |
| 03/02/2001 | Crewe Alexandra | 4 | 2 | Burnley (P) |
| 03/02/2001 | Crystal Palace | 2 | 2 | West Bromwich Albion |
| 03/02/2001 | Huddersfield Town | 1 | 1 | Nottingham Forest |
| 03/02/2001 | Portsmouth | 0 | 1 | Preston North End (P) |
| 03/02/2001 | Queens Park Rangers | 1 | 1 | Bolton Wanderers |
| 03/02/2001 | Sheffield Wednesday (R) | 2 | 3 | Watford (R) |
| 03/02/2001 | Stockport County | 1 | 1 | Tranmere Rovers |
| 03/02/2001 | Wolverhampton Wanderers | 1 | 1 | Gillingham (P) |
| 31/01/2001 | Queens Park Rangers | 0 | 2 | Fulham |
| 27/01/2001 | Fulham | 0 | 1 | Birmingham City |
| 27/01/2001 | Grimsby Town | 2 | 1 | Portsmouth |
| 27/01/2001 | Norwich City | 2 | 1 | Watford (R) |
| 20/01/2001 | Burnley (P) | 2 | 1 | Barnsley |
| 20/01/2001 | Crystal Palace | 2 | 2 | Gillingham (P) |
| 20/01/2001 | Norwich City | 1 | 0 | Queens Park Rangers |
| 20/01/2001 | Portsmouth | 2 | 1 | Wimbledon (R) |
| 20/01/2001 | Sheffield Wednesday (R) | 0 | 3 | Bolton Wanderers |
| 20/01/2001 | Stockport County | 1 | 1 | Grimsby Town |
| 20/01/2001 | Watford (R) | 1 | 3 | Fulham |
| 20/01/2001 | West Bromwich Albion | 2 | 1 | Sheffield United |
| 14/01/2001 | Nottingham Forest | 0 | 3 | Crystal Palace |
| 13/01/2001 | Barnsley | 2 | 3 | Birmingham City |
| 13/01/2001 | Blackburn Rovers | 2 | 0 | Sheffield Wednesday (R) |
| 13/01/2001 | Bolton Wanderers | 2 | 0 | Tranmere Rovers |
| 13/01/2001 | Fulham | 2 | 0 | Norwich City |
| 13/01/2001 | Gillingham (P) | 0 | 0 | Burnley (P) |
| 13/01/2001 | Grimsby Town | 1 | 3 | Crewe Alexandra |
| 13/01/2001 | Huddersfield Town | 0 | 0 | Stockport County |
| 13/01/2001 | Queens Park Rangers | 2 | 0 | West Bromwich Albion |
| 13/01/2001 | Sheffield United | 0 | 1 | Watford (R) |
| 13/01/2001 | Wimbledon (R) | 3 | 1 | Preston North End (P) |
| 13/01/2001 | Wolverhampton Wanderers | 1 | 1 | Portsmouth |
| 10/01/2001 | Blackburn Rovers | 3 | 2 | Preston North End (P) |
| 02/01/2001 | Watford (R) | 3 | 1 | Wimbledon (R) |
| 01/01/2001 | Birmingham City | 0 | 2 | Nottingham Forest |
| 01/01/2001 | Burnley (P) | 1 | 2 | Wolverhampton Wanderers |
| 01/01/2001 | Norwich City | 1 | 1 | Blackburn Rovers |
| 01/01/2001 | Portsmouth | 0 | 0 | Gillingham (P) |
| 01/01/2001 | Preston North End (P) | 0 | 2 | Bolton Wanderers |
| 01/01/2001 | Sheffield Wednesday (R) | 1 | 0 | Grimsby Town |
| 01/01/2001 | Stockport County | 2 | 0 | Fulham |
| 01/01/2001 | Tranmere Rovers | 1 | 0 | Sheffield United |
| 01/01/2001 | West Bromwich Albion | 1 | 0 | Barnsley |
| 30/12/2000 | Blackburn Rovers | 1 | 0 | Crewe Alexandra |
| 30/12/2000 | Bolton Wanderers | 0 | 1 | West Bromwich Albion |
| 30/12/2000 | Huddersfield Town | 0 | 0 | Sheffield Wednesday (R) |
| 30/12/2000 | Nottingham Forest | 0 | 0 | Norwich City |
| 30/12/2000 | Queens Park Rangers | 1 | 1 | Crystal Palace |
| 30/12/2000 | Sheffield United | 3 | 2 | Preston North End (P) |
| 30/12/2000 | Wolverhampton Wanderers | 3 | 2 | Stockport County |
| 29/12/2000 | Barnsley | 0 | 1 | Watford (R) |
| 26/12/2000 | Barnsley | 1 | 0 | Burnley (P) |
| 26/12/2000 | Blackburn Rovers | 2 | 1 | Birmingham City |
| 26/12/2000 | Bolton Wanderers | 2 | 0 | Sheffield Wednesday (R) |
| 26/12/2000 | Fulham | 5 | 0 | Watford (R) |
| 26/12/2000 | Gillingham (P) | 4 | 1 | Crystal Palace |
| 26/12/2000 | Grimsby Town | 1 | 1 | Stockport County |
| 26/12/2000 | Huddersfield Town | 3 | 0 | Tranmere Rovers |
| 26/12/2000 | Nottingham Forest | 1 | 0 | Crewe Alexandra |
| 26/12/2000 | Queens Park Rangers | 2 | 3 | Norwich City |
| 26/12/2000 | Sheffield United | 2 | 0 | West Bromwich Albion |
| 26/12/2000 | Wimbledon (R) | 1 | 1 | Portsmouth |
| 26/12/2000 | Wolverhampton Wanderers | 0 | 1 | Preston North End (P) |
| 23/12/2000 | Birmingham City | 0 | 0 | Queens Park Rangers |
| 23/12/2000 | Burnley (P) | 0 | 2 | Bolton Wanderers |
| 23/12/2000 | Crewe Alexandra | 1 | 2 | Fulham |
| 23/12/2000 | Norwich City | 0 | 0 | Barnsley |
| 23/12/2000 | Portsmouth | 0 | 0 | Sheffield United |
| 23/12/2000 | Preston North End (P) | 1 | 2 | Grimsby Town |
| 23/12/2000 | Sheffield Wednesday (R) | 0 | 1 | Wolverhampton Wanderers |
| 23/12/2000 | Tranmere Rovers | 0 | 4 | Wimbledon (R) |
| 23/12/2000 | Watford (R) | 1 | 2 | Huddersfield Town |
| 23/12/2000 | West Bromwich Albion | 3 | 0 | Nottingham Forest |
| 22/12/2000 | Crystal Palace | 2 | 3 | Blackburn Rovers |
| 22/12/2000 | Stockport County | 2 | 2 | Gillingham (P) |
| 17/12/2000 | Burnley (P) | 0 | 2 | Blackburn Rovers |
| 17/12/2000 | Wolverhampton Wanderers | 0 | 1 | Birmingham City |
| 16/12/2000 | Crewe Alexandra | 1 | 1 | Crystal Palace |
| 16/12/2000 | Fulham | 3 | 1 | Tranmere Rovers |
| 16/12/2000 | Gillingham (P) | 4 | 0 | Preston North End (P) |
| 16/12/2000 | Grimsby Town | 2 | 0 | Norwich City |
| 16/12/2000 | Portsmouth | 1 | 1 | Huddersfield Town |
| 16/12/2000 | Queens Park Rangers | 1 | 0 | Nottingham Forest |
| 16/12/2000 | Sheffield United | 1 | 1 | Sheffield Wednesday (R) |
| 16/12/2000 | Stockport County | 2 | 0 | Barnsley |
| 16/12/2000 | Watford (R) | 3 | 3 | West Bromwich Albion |
| 16/12/2000 | Wimbledon (R) | 0 | 1 | Bolton Wanderers |
| 13/12/2000 | Nottingham Forest | 1 | 3 | Huddersfield Town |
| 13/12/2000 | Wimbledon (R) | 2 | 2 | Grimsby Town |
| 09/12/2000 | Barnsley | 0 | 0 | Sheffield United |
| 09/12/2000 | Birmingham City | 0 | 3 | Wimbledon (R) |
| 09/12/2000 | Blackburn Rovers | 0 | 0 | Queens Park Rangers |
| 09/12/2000 | Bolton Wanderers | 4 | 1 | Crewe Alexandra |
| 09/12/2000 | Crystal Palace | 1 | 0 | Watford (R) |
| 09/12/2000 | Huddersfield Town | 3 | 0 | Wolverhampton Wanderers |
| 09/12/2000 | Norwich City | 1 | 0 | Gillingham (P) |
| 09/12/2000 | Nottingham Forest | 2 | 0 | Portsmouth |
| 09/12/2000 | Preston North End (P) | 2 | 1 | Burnley (P) |
| 09/12/2000 | Sheffield Wednesday (R) | 2 | 4 | Stockport County |
| 09/12/2000 | Tranmere Rovers | 2 | 0 | Grimsby Town |
| 09/12/2000 | West Bromwich Albion | 1 | 3 | Fulham |
| 05/12/2000 | Crystal Palace | 3 | 1 | Wimbledon (R) |
| 03/12/2000 | Bolton Wanderers | 2 | 1 | Watford (R) |
| 02/12/2000 | Burnley (P) | 1 | 0 | Nottingham Forest |
| 02/12/2000 | Gillingham (P) | 1 | 2 | Birmingham City |
| 02/12/2000 | Grimsby Town | 2 | 2 | Crystal Palace |
| 02/12/2000 | Huddersfield Town | 3 | 1 | Crewe Alexandra |
| 02/12/2000 | Portsmouth | 2 | 0 | Norwich City |
| 02/12/2000 | Preston North End (P) | 1 | 1 | Fulham |
| 02/12/2000 | Sheffield Wednesday (R) | 5 | 2 | Queens Park Rangers |
| 02/12/2000 | Stockport County | 0 | 2 | Sheffield United |
| 02/12/2000 | Tranmere Rovers | 1 | 1 | Blackburn Rovers |
| 02/12/2000 | Wimbledon (R) | 0 | 1 | West Bromwich Albion |
| 02/12/2000 | Wolverhampton Wanderers | 2 | 0 | Barnsley |
| 29/11/2000 | Nottingham Forest | 2 | 0 | Sheffield United |
| 25/11/2000 | Barnsley | 1 | 0 | Portsmouth |
| 25/11/2000 | Birmingham City | 2 | 1 | Huddersfield Town |
| 25/11/2000 | Blackburn Rovers | 1 | 2 | Gillingham (P) |
| 25/11/2000 | Crewe Alexandra | 1 | 0 | Sheffield Wednesday (R) |
| 25/11/2000 | Crystal Palace | 2 | 2 | Stockport County |
| 25/11/2000 | Fulham | 2 | 1 | Grimsby Town |
| 25/11/2000 | Norwich City | 1 | 2 | Wimbledon (R) |
| 25/11/2000 | Nottingham Forest | 3 | 1 | Tranmere Rovers |
| 25/11/2000 | Queens Park Rangers | 2 | 2 | Wolverhampton Wanderers |
| 25/11/2000 | Sheffield United | 1 | 0 | Bolton Wanderers |
| 25/11/2000 | West Bromwich Albion | 3 | 1 | Preston North End (P) |
| 21/11/2000 | Burnley (P) | 2 | 0 | Norwich City |
| 21/11/2000 | Sheffield United | 1 | 1 | Fulham |
| 21/11/2000 | Wolverhampton Wanderers | 2 | 0 | Grimsby Town |
| 18/11/2000 | Barnsley | 1 | 0 | Sheffield Wednesday (R) |
| 18/11/2000 | Birmingham City | 3 | 2 | Burnley (P) |
| 18/11/2000 | Blackburn Rovers | 1 | 0 | Wolverhampton Wanderers |
| 18/11/2000 | Crewe Alexandra | 1 | 2 | Stockport County |
| 18/11/2000 | Crystal Palace | 3 | 2 | Tranmere Rovers |
| 18/11/2000 | Fulham | 3 | 1 | Portsmouth |
| 18/11/2000 | Norwich City | 0 | 2 | Bolton Wanderers |
| 18/11/2000 | Nottingham Forest | 1 | 2 | Wimbledon (R) |
| 18/11/2000 | Queens Park Rangers | 1 | 1 | Huddersfield Town |
| 18/11/2000 | Sheffield United | 3 | 2 | Grimsby Town |
| 18/11/2000 | Watford (R) | 2 | 3 | Preston North End (P) |
| 18/11/2000 | West Bromwich Albion | 3 | 1 | Gillingham (P) |
| 12/11/2000 | Gillingham (P) | 1 | 3 | Nottingham Forest |
| 11/11/2000 | Bolton Wanderers | 2 | 0 | Barnsley |
| 11/11/2000 | Burnley (P) | 2 | 0 | Sheffield United |
| 11/11/2000 | Huddersfield Town | 0 | 2 | West Bromwich Albion |
| 11/11/2000 | Portsmouth | 2 | 2 | Blackburn Rovers |
| 11/11/2000 | Sheffield Wednesday (R) | 3 | 2 | Norwich City |
| 11/11/2000 | Stockport County | 2 | 2 | Queens Park Rangers |
| 11/11/2000 | Tranmere Rovers | 2 | 0 | Watford (R) |
| 11/11/2000 | Wimbledon (R) | 0 | 3 | Fulham |
| 11/11/2000 | Wolverhampton Wanderers | 1 | 3 | Crystal Palace |
| 10/11/2000 | Preston North End (P) | 2 | 1 | Crewe Alexandra |
| 08/11/2000 | Barnsley | 1 | 2 | Blackburn Rovers |
| 07/11/2000 | Norwich City | 1 | 0 | Birmingham City |
| 07/11/2000 | Watford (R) | 1 | 3 | Sheffield Wednesday (R) |
| 05/11/2000 | Barnsley | 0 | 1 | Wimbledon (R) |
| 04/11/2000 | Birmingham City | 1 | 1 | Bolton Wanderers |
| 04/11/2000 | Blackburn Rovers | 2 | 1 | Stockport County |
| 04/11/2000 | Crewe Alexandra | 2 | 0 | Wolverhampton Wanderers |
| 04/11/2000 | Crystal Palace | 4 | 1 | Sheffield Wednesday (R) |
| 04/11/2000 | Fulham | 3 | 0 | Huddersfield Town |
| 04/11/2000 | Norwich City | 1 | 0 | Tranmere Rovers |
| 04/11/2000 | Nottingham Forest | 3 | 1 | Preston North End (P) |
| 04/11/2000 | Queens Park Rangers | 1 | 1 | Portsmouth |
| 04/11/2000 | Sheffield United | 1 | 2 | Gillingham (P) |
| 04/11/2000 | Watford (R) | 4 | 0 | Grimsby Town |
| 04/11/2000 | West Bromwich Albion | 1 | 1 | Burnley (P) |
| 31/10/2000 | Bolton Wanderers | 3 | 1 | Queens Park Rangers |
| 31/10/2000 | Burnley (P) | 1 | 0 | Crewe Alexandra |
| 29/10/2000 | Grimsby Town | 2 | 0 | West Bromwich Albion |
| 28/10/2000 | Bolton Wanderers | 3 | 3 | Crystal Palace |
| 28/10/2000 | Gillingham (P) | 0 | 1 | Crewe Alexandra |
| 28/10/2000 | Huddersfield Town | 0 | 1 | Blackburn Rovers |
| 28/10/2000 | Portsmouth | 1 | 1 | Birmingham City |
| 28/10/2000 | Sheffield Wednesday (R) | 3 | 3 | Fulham |
| 28/10/2000 | Stockport County | 1 | 2 | Nottingham Forest |
| 28/10/2000 | Tranmere Rovers | 1 | 1 | Queens Park Rangers |
| 28/10/2000 | Wimbledon (R) | 0 | 0 | Sheffield United |
| 28/10/2000 | Wolverhampton Wanderers | 2 | 2 | Watford (R) |
| 27/10/2000 | Preston North End (P) | 1 | 2 | Barnsley |
| 25/10/2000 | Birmingham City | 1 | 0 | Gillingham (P) |
| 25/10/2000 | Blackburn Rovers | 3 | 2 | Tranmere Rovers |
| 25/10/2000 | Nottingham Forest | 5 | 0 | Burnley (P) |
| 25/10/2000 | Queens Park Rangers | 1 | 2 | Sheffield Wednesday (R) |
| 24/10/2000 | Barnsley | 1 | 2 | Wolverhampton Wanderers |
| 24/10/2000 | Crewe Alexandra | 1 | 0 | Huddersfield Town |
| 24/10/2000 | Crystal Palace | 0 | 1 | Grimsby Town |
| 24/10/2000 | Fulham | 0 | 1 | Preston North End (P) |
| 24/10/2000 | Norwich City | 0 | 0 | Portsmouth |
| 24/10/2000 | Sheffield United | 1 | 0 | Stockport County |
| 24/10/2000 | Watford (R) | 1 | 0 | Bolton Wanderers |
| 24/10/2000 | West Bromwich Albion | 3 | 1 | Wimbledon (R) |
| 22/10/2000 | Sheffield Wednesday (R) | 1 | 0 | Birmingham City |
| 21/10/2000 | Blackburn Rovers | 2 | 0 | Grimsby Town |
| 21/10/2000 | Crewe Alexandra | 0 | 4 | Wimbledon (R) |
| 21/10/2000 | Crystal Palace | 2 | 3 | Portsmouth |
| 21/10/2000 | Gillingham (P) | 0 | 0 | Barnsley |
| 21/10/2000 | Huddersfield Town | 0 | 0 | Preston North End (P) |
| 21/10/2000 | Norwich City | 4 | 2 | Sheffield United |
| 21/10/2000 | Nottingham Forest | 0 | 2 | Watford (R) |
| 21/10/2000 | Queens Park Rangers | 0 | 1 | Burnley (P) |
| 21/10/2000 | Stockport County | 4 | 3 | Bolton Wanderers |
| 21/10/2000 | Tranmere Rovers | 2 | 2 | West Bromwich Albion |
| 21/10/2000 | Wolverhampton Wanderers | 0 | 0 | Fulham |
| 18/10/2000 | Fulham | 3 | 1 | Crystal Palace |
| 18/10/2000 | Wimbledon (R) | 0 | 2 | Blackburn Rovers |
| 17/10/2000 | Barnsley | 1 | 1 | Tranmere Rovers |
| 17/10/2000 | Birmingham City | 4 | 0 | Stockport County |
| 17/10/2000 | Bolton Wanderers | 0 | 0 | Nottingham Forest |
| 17/10/2000 | Burnley (P) | 1 | 0 | Sheffield Wednesday (R) |
| 17/10/2000 | Grimsby Town | 3 | 1 | Queens Park Rangers |
| 17/10/2000 | Portsmouth | 2 | 1 | Crewe Alexandra |
| 17/10/2000 | Preston North End (P) | 1 | 0 | Norwich City |
| 17/10/2000 | Sheffield United | 3 | 0 | Huddersfield Town |
| 17/10/2000 | Watford (R) | 0 | 0 | Gillingham (P) |
| 17/10/2000 | West Bromwich Albion | 1 | 0 | Wolverhampton Wanderers |
| 15/10/2000 | Fulham | 2 | 1 | Blackburn Rovers |
| 14/10/2000 | Barnsley | 3 | 4 | Nottingham Forest |
| 14/10/2000 | Birmingham City | 2 | 1 | Crystal Palace |
| 14/10/2000 | Bolton Wanderers | 2 | 1 | Wolverhampton Wanderers |
| 14/10/2000 | Burnley (P) | 2 | 1 | Stockport County |
| 14/10/2000 | Grimsby Town | 1 | 0 | Huddersfield Town |
| 14/10/2000 | Portsmouth | 2 | 1 | Sheffield Wednesday (R) |
| 14/10/2000 | Preston North End (P) | 1 | 0 | Tranmere Rovers |
| 14/10/2000 | Sheffield United | 1 | 0 | Crewe Alexandra |
| 14/10/2000 | Watford (R) | 3 | 1 | Queens Park Rangers |
| 14/10/2000 | West Bromwich Albion | 2 | 3 | Norwich City |
| 14/10/2000 | Wimbledon (R) | 4 | 4 | Gillingham (P) |
| 08/10/2000 | Crewe Alexandra | 0 | 2 | Birmingham City |
| 08/10/2000 | Sheffield Wednesday (R) | 1 | 2 | West Bromwich Albion |
| 08/10/2000 | Stockport County | 1 | 1 | Portsmouth |
| 06/10/2000 | Gillingham (P) | 2 | 2 | Bolton Wanderers |
| 06/10/2000 | Huddersfield Town | 1 | 1 | Barnsley |
| 06/10/2000 | Tranmere Rovers | 2 | 3 | Burnley (P) |
| 01/10/2000 | Watford (R) | 2 | 0 | Birmingham City |
| 30/09/2000 | Barnsley | 2 | 0 | Grimsby Town |
| 30/09/2000 | Bolton Wanderers | 0 | 2 | Fulham |
| 30/09/2000 | Burnley (P) | 1 | 1 | Portsmouth |
| 30/09/2000 | Gillingham (P) | 2 | 0 | Sheffield Wednesday (R) |
| 30/09/2000 | Norwich City | 1 | 1 | Huddersfield Town |
| 30/09/2000 | Nottingham Forest | 0 | 0 | Wolverhampton Wanderers |
| 30/09/2000 | Preston North End (P) | 2 | 0 | Crystal Palace |
| 30/09/2000 | Sheffield United | 1 | 1 | Queens Park Rangers |
| 30/09/2000 | Tranmere Rovers | 1 | 3 | Crewe Alexandra |
| 30/09/2000 | West Bromwich Albion | 1 | 0 | Blackburn Rovers |
| 30/09/2000 | Wimbledon (R) | 2 | 0 | Stockport County |
| 24/09/2000 | Wolverhampton Wanderers | 4 | 0 | Norwich City |
| 23/09/2000 | Birmingham City | 2 | 0 | Tranmere Rovers |
| 23/09/2000 | Blackburn Rovers | 1 | 1 | Bolton Wanderers |
| 23/09/2000 | Crewe Alexandra | 2 | 2 | Barnsley |
| 23/09/2000 | Crystal Palace | 0 | 1 | Sheffield United |
| 23/09/2000 | Fulham | 3 | 0 | Gillingham (P) |
| 23/09/2000 | Grimsby Town | 0 | 2 | Nottingham Forest |
| 23/09/2000 | Huddersfield Town | 0 | 1 | Burnley (P) |
| 23/09/2000 | Portsmouth | 0 | 1 | West Bromwich Albion |
| 23/09/2000 | Queens Park Rangers | 2 | 1 | Wimbledon (R) |
| 23/09/2000 | Sheffield Wednesday (R) | 1 | 3 | Preston North End (P) |
| 23/09/2000 | Stockport County | 2 | 3 | Watford (R) |
| 17/09/2000 | West Bromwich Albion | 1 | 1 | Birmingham City |
| 16/09/2000 | Barnsley | 4 | 2 | Queens Park Rangers |
| 16/09/2000 | Bolton Wanderers | 2 | 0 | Portsmouth |
| 16/09/2000 | Burnley (P) | 1 | 1 | Grimsby Town |
| 16/09/2000 | Gillingham (P) | 2 | 1 | Huddersfield Town |
| 16/09/2000 | Norwich City | 0 | 0 | Crystal Palace |
| 16/09/2000 | Nottingham Forest | 0 | 3 | Fulham |
| 16/09/2000 | Preston North End (P) | 1 | 1 | Stockport County |
| 16/09/2000 | Tranmere Rovers | 2 | 0 | Sheffield Wednesday (R) |
| 16/09/2000 | Watford (R) | 3 | 0 | Crewe Alexandra |
| 16/09/2000 | Wimbledon (R) | 1 | 1 | Wolverhampton Wanderers |
| 15/09/2000 | Sheffield United | 2 | 0 | Blackburn Rovers |
| 13/09/2000 | Queens Park Rangers | 2 | 2 | Gillingham (P) |
| 13/09/2000 | Sheffield Wednesday (R) | 0 | 1 | Nottingham Forest |
| 12/09/2000 | Birmingham City | 3 | 1 | Preston North End (P) |
| 12/09/2000 | Blackburn Rovers | 3 | 4 | Watford (R) |
| 12/09/2000 | Crewe Alexandra | 0 | 1 | West Bromwich Albion |
| 12/09/2000 | Crystal Palace | 1 | 0 | Barnsley |
| 12/09/2000 | Fulham | 3 | 1 | Burnley (P) |
| 12/09/2000 | Grimsby Town | 0 | 1 | Bolton Wanderers |
| 12/09/2000 | Huddersfield Town | 0 | 2 | Wimbledon (R) |
| 12/09/2000 | Portsmouth | 2 | 0 | Tranmere Rovers |
| 12/09/2000 | Stockport County | 1 | 3 | Norwich City |
| 12/09/2000 | Wolverhampton Wanderers | 0 | 0 | Sheffield United |
| 10/09/2000 | Fulham | 5 | 1 | Barnsley |
| 09/09/2000 | Birmingham City | 1 | 0 | Sheffield United |
| 09/09/2000 | Blackburn Rovers | 3 | 0 | Nottingham Forest |
| 09/09/2000 | Crewe Alexandra | 0 | 0 | Norwich City |
| 09/09/2000 | Crystal Palace | 0 | 1 | Burnley (P) |
| 09/09/2000 | Grimsby Town | 1 | 0 | Gillingham (P) |
| 09/09/2000 | Huddersfield Town | 2 | 3 | Bolton Wanderers |
| 09/09/2000 | Portsmouth | 1 | 3 | Watford (R) |
| 09/09/2000 | Queens Park Rangers | 0 | 0 | Preston North End (P) |
| 09/09/2000 | Sheffield Wednesday (R) | 0 | 5 | Wimbledon (R) |
| 09/09/2000 | Stockport County | 0 | 0 | West Bromwich Albion |
| 09/09/2000 | Wolverhampton Wanderers | 1 | 2 | Tranmere Rovers |
| 03/09/2000 | West Bromwich Albion | 1 | 0 | Crystal Palace |
| 02/09/2000 | Gillingham (P) | 1 | 0 | Wolverhampton Wanderers |
| 02/09/2000 | Preston North End (P) | 1 | 0 | Portsmouth |
| 01/09/2000 | Tranmere Rovers | 2 | 1 | Stockport County |
| 29/08/2000 | Crewe Alexandra | 2 | 0 | Grimsby Town |
| 28/08/2000 | Birmingham City | 4 | 1 | Barnsley |
| 28/08/2000 | Burnley (P) | 1 | 1 | Gillingham (P) |
| 28/08/2000 | Crystal Palace | 2 | 3 | Nottingham Forest |
| 28/08/2000 | Norwich City | 0 | 1 | Fulham |
| 28/08/2000 | Portsmouth | 3 | 1 | Wolverhampton Wanderers |
| 28/08/2000 | Preston North End (P) | 1 | 1 | Wimbledon (R) |
| 28/08/2000 | Sheffield Wednesday (R) | 1 | 1 | Blackburn Rovers |
| 28/08/2000 | Stockport County | 0 | 0 | Huddersfield Town |
| 28/08/2000 | Tranmere Rovers | 0 | 1 | Bolton Wanderers |
| 28/08/2000 | Watford (R) | 4 | 1 | Sheffield United |
| 28/08/2000 | West Bromwich Albion | 2 | 1 | Queens Park Rangers |
| 26/08/2000 | Barnsley | 4 | 1 | West Bromwich Albion |
| 26/08/2000 | Blackburn Rovers | 3 | 2 | Norwich City |
| 26/08/2000 | Bolton Wanderers | 2 | 0 | Preston North End (P) |
| 26/08/2000 | Fulham | 4 | 1 | Stockport County |
| 26/08/2000 | Grimsby Town | 0 | 1 | Sheffield Wednesday (R) |
| 26/08/2000 | Huddersfield Town | 1 | 2 | Crystal Palace |
| 26/08/2000 | Nottingham Forest | 1 | 2 | Birmingham City |
| 26/08/2000 | Queens Park Rangers | 1 | 0 | Crewe Alexandra |
| 26/08/2000 | Sheffield United | 2 | 0 | Tranmere Rovers |
| 26/08/2000 | Wimbledon (R) | 0 | 0 | Watford (R) |
| 26/08/2000 | Wolverhampton Wanderers | 1 | 0 | Burnley (P) |
| 25/08/2000 | Gillingham (P) | 1 | 1 | Portsmouth |
| 20/08/2000 | Crystal Palace | 1 | 1 | Queens Park Rangers |
| 19/08/2000 | Burnley (P) | 1 | 0 | Wimbledon (R) |
| 19/08/2000 | Crewe Alexandra | 0 | 0 | Blackburn Rovers |
| 19/08/2000 | Norwich City | 0 | 0 | Nottingham Forest |
| 19/08/2000 | Portsmouth | 1 | 1 | Grimsby Town |
| 19/08/2000 | Preston North End (P) | 3 | 0 | Sheffield United |
| 19/08/2000 | Sheffield Wednesday (R) | 2 | 3 | Huddersfield Town |
| 19/08/2000 | Stockport County | 1 | 1 | Wolverhampton Wanderers |
| 19/08/2000 | Tranmere Rovers | 3 | 2 | Gillingham (P) |
| 19/08/2000 | Watford (R) | 1 | 0 | Barnsley |
| 19/08/2000 | West Bromwich Albion | 0 | 2 | Bolton Wanderers |
| 18/08/2000 | Birmingham City | 1 | 3 | Fulham |
| 13/08/2000 | Wolverhampton Wanderers | 1 | 1 | Sheffield Wednesday (R) |
| 12/08/2000 | Barnsley | 1 | 0 | Norwich City |
| 12/08/2000 | Blackburn Rovers | 2 | 0 | Crystal Palace |
| 12/08/2000 | Bolton Wanderers | 1 | 1 | Burnley (P) |
| 12/08/2000 | Fulham | 2 | 0 | Crewe Alexandra |
| 12/08/2000 | Gillingham (P) | 1 | 3 | Stockport County |
| 12/08/2000 | Grimsby Town | 1 | 2 | Preston North End (P) |
| 12/08/2000 | Huddersfield Town | 1 | 2 | Watford (R) |
| 12/08/2000 | Nottingham Forest | 1 | 0 | West Bromwich Albion |
| 12/08/2000 | Queens Park Rangers | 0 | 0 | Birmingham City |
| 12/08/2000 | Sheffield United | 2 | 0 | Portsmouth |
| 12/08/2000 | Wimbledon (R) | 0 | 0 | Tranmere Rovers |