| Hellenic Premier | ||||
| Date | Home | H | A | Away |
| 15/05/2001 | Abingdon United | 3 | 1 | North Leigh |
| 15/05/2001 | Yate Town (R) | 0 | 0 | Tuffley Rovers |
| 14/05/2001 | Cirencester Academy | 2 | 0 | Milton United |
| 14/05/2001 | Tuffley Rovers | 5 | 1 | Pegasus Juniors |
| 11/05/2001 | Bicester Town | 1 | 3 | Wootton Bassett Town (P) |
| 11/05/2001 | Cirencester Academy | 1 | 0 | North Leigh |
| 11/05/2001 | Pegasus Juniors | 3 | 1 | Carterton Town |
| 11/05/2001 | Tuffley Rovers | 1 | 0 | Didcot Town |
| 11/05/2001 | Wantage Town | 1 | 0 | Cheltenham Saracens (P) |
| 10/05/2001 | Harrow Hill | 1 | 2 | Shortwood United |
| 10/05/2001 | Yate Town (R) | 3 | 0 | Highworth Town |
| 09/05/2001 | Bicester Town | 0 | 1 | North Leigh |
| 09/05/2001 | Brackley Town | 3 | 0 | Wootton Bassett Town (P) |
| 09/05/2001 | Carterton Town | 2 | 3 | Fairford Town |
| 09/05/2001 | Cirencester Academy | 4 | 1 | Tuffley Rovers |
| 09/05/2001 | Milton United | 1 | 0 | Abingdon United |
| 09/05/2001 | Pegasus Juniors | 5 | 0 | Cheltenham Saracens (P) |
| 09/05/2001 | Swindon Supermarine | 2 | 1 | Shortwood United |
| 08/05/2001 | Cirencester Academy | 2 | 2 | Wantage Town |
| 08/05/2001 | Pegasus Juniors | 7 | 3 | Bicester Town |
| 07/05/2001 | Carterton Town | 1 | 1 | Harrow Hill |
| 07/05/2001 | Cheltenham Saracens (P) | 0 | 1 | Abingdon United |
| 07/05/2001 | Cirencester Academy | 3 | 1 | Fairford Town |
| 07/05/2001 | Milton United | 2 | 0 | Tuffley Rovers |
| 07/05/2001 | North Leigh | 3 | 1 | Shortwood United |
| 07/05/2001 | Pegasus Juniors | 4 | 3 | Brackley Town |
| 07/05/2001 | Swindon Supermarine | 2 | 2 | Bicester Town |
| 05/05/2001 | Carterton Town | 2 | 0 | Cirencester Academy |
| 05/05/2001 | Cheltenham Saracens (P) | 0 | 3 | Bicester Town |
| 05/05/2001 | Didcot Town | 2 | 1 | Swindon Supermarine |
| 05/05/2001 | North Leigh | 2 | 0 | Wootton Bassett Town (P) |
| 05/05/2001 | Shortwood United | 2 | 1 | Milton United |
| 05/05/2001 | Tuffley Rovers | 2 | 5 | Brackley Town |
| 05/05/2001 | Yate Town (R) | 6 | 0 | Pegasus Juniors |
| 03/05/2001 | Brackley Town | 0 | 0 | Yate Town (R) |
| 03/05/2001 | Carterton Town | 2 | 2 | Shortwood United |
| 03/05/2001 | Fairford Town | 1 | 0 | Didcot Town |
| 03/05/2001 | Pegasus Juniors | 2 | 0 | Cirencester Academy |
| 03/05/2001 | Tuffley Rovers | 1 | 2 | Abingdon United |
| 02/05/2001 | Almondsbury Town | 2 | 1 | Highworth Town |
| 02/05/2001 | Cheltenham Saracens (P) | 3 | 0 | Shortwood United |
| 02/05/2001 | Cirencester Academy | 2 | 2 | Carterton Town |
| 02/05/2001 | Swindon Supermarine | 4 | 0 | Tuffley Rovers |
| 01/05/2001 | Milton United | 0 | 3 | North Leigh |
| 01/05/2001 | Pegasus Juniors | 2 | 2 | Abingdon United |
| 01/05/2001 | Shortwood United | 1 | 1 | Swindon Supermarine |
| 01/05/2001 | Tuffley Rovers | 1 | 2 | Carterton Town |
| 01/05/2001 | Wootton Bassett Town (P) | 1 | 1 | Yate Town (R) |
| 30/04/2001 | Cheltenham Saracens (P) | 0 | 2 | Cirencester Academy |
| 30/04/2001 | Shortwood United | 2 | 0 | Pegasus Juniors |
| 28/04/2001 | Abingdon United | 8 | 2 | Almondsbury Town |
| 28/04/2001 | Cheltenham Saracens (P) | 0 | 2 | Highworth Town |
| 28/04/2001 | Cirencester Academy | 1 | 2 | Brackley Town |
| 28/04/2001 | Fairford Town | 0 | 0 | Shortwood United |
| 28/04/2001 | Milton United | 2 | 3 | Yate Town (R) |
| 28/04/2001 | North Leigh | 2 | 1 | Swindon Supermarine |
| 28/04/2001 | Wantage Town | 3 | 1 | Harrow Hill |
| 28/04/2001 | Wootton Bassett Town (P) | 2 | 0 | Carterton Town |
| 26/04/2001 | Abingdon United | 3 | 1 | Tuffley Rovers |
| 26/04/2001 | Fairford Town | 0 | 2 | Brackley Town |
| 26/04/2001 | Harrow Hill | 1 | 5 | Yate Town (R) |
| 26/04/2001 | North Leigh | 0 | 1 | Cheltenham Saracens (P) |
| 26/04/2001 | Wootton Bassett Town (P) | 1 | 3 | Cirencester Academy |
| 25/04/2001 | North Leigh | 7 | 2 | Pegasus Juniors |
| 24/04/2001 | Abingdon United | 5 | 2 | Milton United |
| 24/04/2001 | Didcot Town | 2 | 2 | Brackley Town |
| 23/04/2001 | Highworth Town | 3 | 0 | Pegasus Juniors |
| 23/04/2001 | Shortwood United | 1 | 1 | Yate Town (R) |
| 23/04/2001 | Swindon Supermarine | 3 | 1 | Cheltenham Saracens (P) |
| 23/04/2001 | Tuffley Rovers | 0 | 0 | Cirencester Academy |
| 23/04/2001 | Wantage Town | 3 | 2 | Bicester Town |
| 21/04/2001 | Almondsbury Town | 0 | 1 | Swindon Supermarine |
| 21/04/2001 | Carterton Town | 0 | 3 | Milton United |
| 21/04/2001 | Didcot Town | 1 | 0 | Pegasus Juniors |
| 21/04/2001 | Harrow Hill | 0 | 5 | Brackley Town |
| 21/04/2001 | Highworth Town | 1 | 5 | Abingdon United |
| 21/04/2001 | Shortwood United | 3 | 1 | Bicester Town |
| 21/04/2001 | Tuffley Rovers | 0 | 2 | Fairford Town |
| 21/04/2001 | Wantage Town | 1 | 2 | Yate Town (R) |
| 21/04/2001 | Wootton Bassett Town (P) | 1 | 0 | North Leigh |
| 19/04/2001 | Milton United | 1 | 1 | Shortwood United |
| 19/04/2001 | Pegasus Juniors | 0 | 1 | Wootton Bassett Town (P) |
| 19/04/2001 | Yate Town (R) | 2 | 0 | Cirencester Academy |
| 18/04/2001 | Bicester Town | 2 | 2 | Highworth Town |
| 18/04/2001 | Cheltenham Saracens (P) | 1 | 1 | Tuffley Rovers |
| 18/04/2001 | North Leigh | 1 | 0 | Abingdon United |
| 16/04/2001 | Brackley Town | 2 | 0 | Bicester Town |
| 16/04/2001 | Cirencester Academy | 3 | 2 | Highworth Town |
| 16/04/2001 | Harrow Hill | 3 | 0 | North Leigh |
| 16/04/2001 | Milton United | 1 | 2 | Pegasus Juniors |
| 16/04/2001 | Wantage Town | 1 | 4 | Tuffley Rovers |
| 16/04/2001 | Yate Town (R) | 3 | 0 | Cheltenham Saracens (P) |
| 14/04/2001 | Abingdon United | 2 | 1 | Cirencester Academy |
| 14/04/2001 | Bicester Town | 2 | 1 | Shortwood United |
| 14/04/2001 | Carterton Town | 3 | 1 | Almondsbury Town |
| 14/04/2001 | Cheltenham Saracens (P) | 0 | 4 | Brackley Town |
| 14/04/2001 | Didcot Town | 3 | 1 | Harrow Hill |
| 14/04/2001 | Highworth Town | 1 | 0 | Tuffley Rovers |
| 14/04/2001 | Pegasus Juniors | 1 | 2 | North Leigh |
| 14/04/2001 | Swindon Supermarine | 0 | 0 | Yate Town (R) |
| 12/04/2001 | Cirencester Academy | 0 | 3 | Bicester Town |
| 12/04/2001 | Highworth Town | 0 | 3 | North Leigh |
| 12/04/2001 | Pegasus Juniors | 0 | 2 | Yate Town (R) |
| 11/04/2001 | Cheltenham Saracens (P) | 1 | 2 | Fairford Town |
| 11/04/2001 | Shortwood United | 3 | 2 | Almondsbury Town |
| 10/04/2001 | Carterton Town | 2 | 2 | Wantage Town |
| 10/04/2001 | Didcot Town | 2 | 0 | Yate Town (R) |
| 10/04/2001 | Harrow Hill | 1 | 4 | Highworth Town |
| 10/04/2001 | Swindon Supermarine | 8 | 1 | Pegasus Juniors |
| 07/04/2001 | Abingdon United | 1 | 1 | Didcot Town |
| 07/04/2001 | Bicester Town | 1 | 1 | Almondsbury Town |
| 07/04/2001 | Brackley Town | 1 | 1 | Harrow Hill |
| 07/04/2001 | Carterton Town | 0 | 1 | Cheltenham Saracens (P) |
| 07/04/2001 | Highworth Town | 2 | 8 | Yate Town (R) |
| 07/04/2001 | North Leigh | 4 | 1 | Fairford Town |
| 07/04/2001 | Pegasus Juniors | 3 | 4 | Wantage Town |
| 03/04/2001 | Abingdon United | 3 | 3 | Carterton Town |
| 03/04/2001 | Brackley Town | 2 | 1 | Wantage Town |
| 03/04/2001 | Wootton Bassett Town (P) | 3 | 1 | Bicester Town |
| 31/03/2001 | Almondsbury Town | 1 | 1 | Carterton Town |
| 31/03/2001 | Brackley Town | 2 | 0 | Tuffley Rovers |
| 31/03/2001 | Cheltenham Saracens (P) | 1 | 4 | Didcot Town |
| 31/03/2001 | Fairford Town | 1 | 3 | Highworth Town |
| 31/03/2001 | Milton United | 0 | 5 | Cirencester Academy |
| 31/03/2001 | North Leigh | 2 | 1 | Harrow Hill |
| 31/03/2001 | Wantage Town | 2 | 0 | Shortwood United |
| 31/03/2001 | Wootton Bassett Town (P) | 0 | 1 | Swindon Supermarine |
| 31/03/2001 | Yate Town (R) | 1 | 0 | Bicester Town |
| 27/03/2001 | Wootton Bassett Town (P) | 2 | 3 | Tuffley Rovers |
| 24/03/2001 | Abingdon United | 5 | 1 | Harrow Hill |
| 24/03/2001 | Milton United | 1 | 3 | Fairford Town |
| 20/03/2001 | Bicester Town | 2 | 1 | Carterton Town |
| 20/03/2001 | Brackley Town | 1 | 1 | Didcot Town |
| 17/03/2001 | Wantage Town | 2 | 1 | Almondsbury Town |
| 14/03/2001 | Cheltenham Saracens (P) | 1 | 0 | Almondsbury Town |
| 14/03/2001 | North Leigh | 1 | 3 | Cirencester Academy |
| 14/03/2001 | Shortwood United | 2 | 0 | Harrow Hill |
| 13/03/2001 | Abingdon United | 2 | 2 | Brackley Town |
| 13/03/2001 | Didcot Town | 0 | 1 | Carterton Town |
| 13/03/2001 | Wantage Town | 0 | 2 | Swindon Supermarine |
| 10/03/2001 | Abingdon United | 2 | 1 | Highworth Town |
| 10/03/2001 | Almondsbury Town | 0 | 2 | Cirencester Academy |
| 10/03/2001 | Brackley Town | 3 | 2 | Pegasus Juniors |
| 10/03/2001 | Didcot Town | 1 | 2 | Shortwood United |
| 10/03/2001 | Fairford Town | 3 | 0 | Bicester Town |
| 10/03/2001 | North Leigh | 8 | 1 | Milton United |
| 10/03/2001 | Tuffley Rovers | 1 | 0 | Wantage Town |
| 10/03/2001 | Wootton Bassett Town (P) | 3 | 0 | Cheltenham Saracens (P) |
| 07/03/2001 | Cirencester Academy | 4 | 1 | Wootton Bassett Town (P) |
| 07/03/2001 | North Leigh | 4 | 0 | Highworth Town |
| 06/03/2001 | Bicester Town | 3 | 1 | Abingdon United |
| 06/03/2001 | Carterton Town | 1 | 2 | Tuffley Rovers |
| 06/03/2001 | Swindon Supermarine | 2 | 1 | Didcot Town |
| 03/03/2001 | Almondsbury Town | 0 | 2 | Didcot Town |
| 03/03/2001 | Bicester Town | 2 | 1 | Tuffley Rovers |
| 03/03/2001 | Highworth Town | 0 | 1 | Cirencester Academy |
| 03/03/2001 | Milton United | 2 | 1 | Harrow Hill |
| 03/03/2001 | Shortwood United | 1 | 3 | Abingdon United |
| 03/03/2001 | Swindon Supermarine | 0 | 2 | North Leigh |
| 03/03/2001 | Wantage Town | 1 | 4 | Fairford Town |
| 03/03/2001 | Yate Town (R) | 0 | 2 | Carterton Town |
| 28/02/2001 | Fairford Town | 1 | 0 | Abingdon United |
| 28/02/2001 | Pegasus Juniors | 4 | 1 | Almondsbury Town |
| 27/02/2001 | Bicester Town | 2 | 3 | Milton United |
| 27/02/2001 | Carterton Town | 4 | 1 | Brackley Town |
| 27/02/2001 | Didcot Town | 2 | 0 | Wantage Town |
| 27/02/2001 | Swindon Supermarine | 3 | 0 | Harrow Hill |
| 27/02/2001 | Tuffley Rovers | 1 | 1 | North Leigh |
| 27/02/2001 | Wootton Bassett Town (P) | 2 | 3 | Shortwood United |
| 24/02/2001 | Abingdon United | 2 | 0 | Cheltenham Saracens (P) |
| 24/02/2001 | Brackley Town | 3 | 0 | Almondsbury Town |
| 24/02/2001 | Carterton Town | 2 | 1 | Swindon Supermarine |
| 24/02/2001 | Cirencester Academy | 1 | 2 | Shortwood United |
| 24/02/2001 | Fairford Town | 0 | 1 | Wantage Town |
| 24/02/2001 | Harrow Hill | 0 | 0 | Wootton Bassett Town (P) |
| 24/02/2001 | Highworth Town | 0 | 2 | Bicester Town |
| 24/02/2001 | North Leigh | 1 | 1 | Yate Town (R) |
| 24/02/2001 | Pegasus Juniors | 1 | 1 | Didcot Town |
| 24/02/2001 | Tuffley Rovers | 2 | 1 | Milton United |
| 21/02/2001 | Cheltenham Saracens (P) | 2 | 1 | Pegasus Juniors |
| 21/02/2001 | Cirencester Academy | 2 | 4 | Abingdon United |
| 21/02/2001 | Fairford Town | 1 | 1 | Harrow Hill |
| 21/02/2001 | Shortwood United | 3 | 1 | Wantage Town |
| 20/02/2001 | Brackley Town | 3 | 0 | Milton United |
| 20/02/2001 | Swindon Supermarine | 2 | 1 | Wootton Bassett Town (P) |
| 17/02/2001 | Almondsbury Town | 1 | 3 | Abingdon United |
| 17/02/2001 | Bicester Town | 5 | 3 | Pegasus Juniors |
| 17/02/2001 | Cheltenham Saracens (P) | 2 | 2 | Milton United |
| 17/02/2001 | Didcot Town | 0 | 1 | Tuffley Rovers |
| 17/02/2001 | Shortwood United | 2 | 1 | Carterton Town |
| 17/02/2001 | Swindon Supermarine | 1 | 0 | Fairford Town |
| 17/02/2001 | Wantage Town | 2 | 3 | North Leigh |
| 17/02/2001 | Wootton Bassett Town (P) | 1 | 1 | Brackley Town |
| 17/02/2001 | Yate Town (R) | 6 | 0 | Harrow Hill |
| 14/02/2001 | Fairford Town | 0 | 0 | Carterton Town |
| 14/02/2001 | North Leigh | 2 | 2 | Brackley Town |
| 14/02/2001 | Shortwood United | 3 | 0 | Highworth Town |
| 13/02/2001 | Almondsbury Town | 2 | 1 | Milton United |
| 13/02/2001 | Didcot Town | 2 | 2 | Bicester Town |
| 10/02/2001 | Abingdon United | 2 | 0 | Wantage Town |
| 10/02/2001 | Brackley Town | 2 | 0 | Shortwood United |
| 10/02/2001 | Carterton Town | 1 | 0 | Highworth Town |
| 10/02/2001 | Cirencester Academy | 0 | 2 | Yate Town (R) |
| 10/02/2001 | Fairford Town | 1 | 0 | Almondsbury Town |
| 10/02/2001 | Harrow Hill | 1 | 2 | Didcot Town |
| 10/02/2001 | Milton United | 0 | 6 | Swindon Supermarine |
| 10/02/2001 | Tuffley Rovers | 1 | 2 | Bicester Town |
| 03/02/2001 | Almondsbury Town | 0 | 4 | North Leigh |
| 03/02/2001 | Carterton Town | 3 | 0 | Bicester Town |
| 03/02/2001 | Cheltenham Saracens (P) | 2 | 1 | Wantage Town |
| 03/02/2001 | Didcot Town | 1 | 1 | Cirencester Academy |
| 03/02/2001 | Highworth Town | 2 | 4 | Brackley Town |
| 03/02/2001 | Pegasus Juniors | 0 | 0 | Milton United |
| 03/02/2001 | Wootton Bassett Town (P) | 0 | 0 | Fairford Town |
| 03/02/2001 | Yate Town (R) | 6 | 0 | Abingdon United |
| 31/01/2001 | Harrow Hill | 2 | 0 | Pegasus Juniors |
| 31/01/2001 | Highworth Town | 1 | 2 | Didcot Town |
| 31/01/2001 | North Leigh | 6 | 1 | Carterton Town |
| 31/01/2001 | Shortwood United | 4 | 2 | Cirencester Academy |
| 30/01/2001 | Abingdon United | 0 | 2 | Swindon Supermarine |
| 30/01/2001 | Almondsbury Town | 0 | 1 | Tuffley Rovers |
| 30/01/2001 | Wootton Bassett Town (P) | 2 | 0 | Wantage Town |
| 27/01/2001 | Bicester Town | 1 | 3 | Fairford Town |
| 27/01/2001 | Harrow Hill | 0 | 0 | Cheltenham Saracens (P) |
| 23/01/2001 | Didcot Town | 0 | 0 | Wootton Bassett Town (P) |
| 20/01/2001 | Swindon Supermarine | 3 | 0 | Brackley Town |
| 20/01/2001 | Yate Town (R) | 2 | 1 | Fairford Town |
| 13/01/2001 | Almondsbury Town | 0 | 1 | Brackley Town |
| 13/01/2001 | Bicester Town | 0 | 1 | Harrow Hill |
| 13/01/2001 | Cheltenham Saracens (P) | 0 | 7 | Yate Town (R) |
| 13/01/2001 | Cirencester Academy | 0 | 1 | Swindon Supermarine |
| 13/01/2001 | Didcot Town | 2 | 0 | North Leigh |
| 13/01/2001 | Fairford Town | 3 | 0 | Milton United |
| 13/01/2001 | Highworth Town | 2 | 1 | Shortwood United |
| 13/01/2001 | Tuffley Rovers | 1 | 1 | Wootton Bassett Town (P) |
| 13/01/2001 | Wantage Town | 0 | 2 | Abingdon United |
| 09/01/2001 | Almondsbury Town | 0 | 1 | Pegasus Juniors |
| 09/01/2001 | Brackley Town | 3 | 0 | Carterton Town |
| 06/01/2001 | Abingdon United | 1 | 2 | Wootton Bassett Town (P) |
| 06/01/2001 | Brackley Town | 4 | 2 | Highworth Town |
| 06/01/2001 | Harrow Hill | 1 | 2 | Almondsbury Town |
| 06/01/2001 | Milton United | 0 | 1 | Didcot Town |
| 06/01/2001 | Tuffley Rovers | 2 | 0 | Cheltenham Saracens (P) |
| 26/12/2000 | Highworth Town | 1 | 2 | Swindon Supermarine |
| 26/12/2000 | Tuffley Rovers | 1 | 1 | Shortwood United |
| 26/12/2000 | Yate Town (R) | 4 | 0 | Almondsbury Town |
| 23/12/2000 | Abingdon United | 2 | 1 | Yate Town (R) |
| 23/12/2000 | Brackley Town | 3 | 1 | Fairford Town |
| 23/12/2000 | Milton United | 1 | 2 | Wantage Town |
| 19/12/2000 | Carterton Town | 1 | 1 | Wootton Bassett Town (P) |
| 16/12/2000 | Bicester Town | 1 | 4 | Swindon Supermarine |
| 16/12/2000 | Carterton Town | 3 | 0 | Pegasus Juniors |
| 16/12/2000 | Didcot Town | 1 | 1 | Fairford Town |
| 16/12/2000 | Shortwood United | 2 | 2 | Cheltenham Saracens (P) |
| 16/12/2000 | Wantage Town | 3 | 2 | Wootton Bassett Town (P) |
| 09/12/2000 | Almondsbury Town | 2 | 1 | Shortwood United |
| 09/12/2000 | Swindon Supermarine | 3 | 2 | Abingdon United |
| 09/12/2000 | Wantage Town | 3 | 5 | Brackley Town |
| 05/12/2000 | Didcot Town | 3 | 0 | Milton United |
| 02/12/2000 | Bicester Town | 3 | 0 | Cirencester Academy |
| 02/12/2000 | Cheltenham Saracens (P) | 3 | 1 | Harrow Hill |
| 02/12/2000 | Fairford Town | 2 | 3 | Pegasus Juniors |
| 02/12/2000 | Highworth Town | 2 | 1 | Almondsbury Town |
| 02/12/2000 | Wantage Town | 2 | 3 | Carterton Town |
| 02/12/2000 | Yate Town (R) | 5 | 0 | Brackley Town |
| 29/11/2000 | Highworth Town | 4 | 2 | Harrow Hill |
| 18/11/2000 | Almondsbury Town | 1 | 2 | Wantage Town |
| 18/11/2000 | Brackley Town | 2 | 0 | Cheltenham Saracens (P) |
| 18/11/2000 | Fairford Town | 1 | 3 | Tuffley Rovers |
| 18/11/2000 | Harrow Hill | 1 | 2 | Swindon Supermarine |
| 18/11/2000 | Shortwood United | 0 | 0 | Didcot Town |
| 18/11/2000 | Yate Town (R) | 3 | 1 | Milton United |
| 14/11/2000 | Carterton Town | 1 | 1 | Didcot Town |
| 11/11/2000 | Didcot Town | 3 | 1 | Almondsbury Town |
| 11/11/2000 | Tuffley Rovers | 3 | 2 | Harrow Hill |
| 08/11/2000 | Shortwood United | 1 | 1 | Fairford Town |
| 04/11/2000 | Abingdon United | 2 | 0 | Shortwood United |
| 04/11/2000 | Bicester Town | 2 | 0 | Cheltenham Saracens (P) |
| 04/11/2000 | Harrow Hill | 0 | 2 | Carterton Town |
| 04/11/2000 | Highworth Town | 2 | 1 | Wantage Town |
| 04/11/2000 | Swindon Supermarine | 4 | 0 | Milton United |
| 04/11/2000 | Wootton Bassett Town (P) | 4 | 3 | Pegasus Juniors |
| 04/11/2000 | Yate Town (R) | 1 | 1 | Didcot Town |
| 01/11/2000 | Harrow Hill | 0 | 0 | Fairford Town |
| 31/10/2000 | Bicester Town | 0 | 1 | Didcot Town |
| 31/10/2000 | Carterton Town | 1 | 2 | Abingdon United |
| 21/10/2000 | Brackley Town | 2 | 1 | North Leigh |
| 21/10/2000 | Milton United | 0 | 1 | Wootton Bassett Town (P) |
| 17/10/2000 | Almondsbury Town | 2 | 2 | Wootton Bassett Town (P) |
| 14/10/2000 | Fairford Town | 1 | 2 | North Leigh |
| 14/10/2000 | Milton United | 1 | 5 | Highworth Town |
| 14/10/2000 | Shortwood United | 1 | 2 | Brackley Town |
| 14/10/2000 | Swindon Supermarine | 3 | 0 | Carterton Town |
| 11/10/2000 | Fairford Town | 2 | 1 | Yate Town (R) |
| 10/10/2000 | Abingdon United | 2 | 2 | Bicester Town |
| 10/10/2000 | Almondsbury Town | 2 | 3 | Harrow Hill |
| 10/10/2000 | Didcot Town | 4 | 1 | Highworth Town |
| 10/10/2000 | Milton United | 1 | 2 | Carterton Town |
| 10/10/2000 | Wantage Town | 1 | 4 | Cirencester Academy |
| 07/10/2000 | Brackley Town | 1 | 2 | Swindon Supermarine |
| 07/10/2000 | Cirencester Academy | 4 | 0 | Cheltenham Saracens (P) |
| 07/10/2000 | Harrow Hill | 1 | 0 | Milton United |
| 07/10/2000 | Highworth Town | 2 | 1 | Fairford Town |
| 07/10/2000 | North Leigh | 1 | 0 | Almondsbury Town |
| 07/10/2000 | Pegasus Juniors | 4 | 3 | Tuffley Rovers |
| 07/10/2000 | Wootton Bassett Town (P) | 2 | 1 | Abingdon United |
| 07/10/2000 | Yate Town (R) | 7 | 0 | Wantage Town |
| 04/10/2000 | Cirencester Academy | 4 | 2 | Almondsbury Town |
| 30/09/2000 | Pegasus Juniors | 2 | 3 | Highworth Town |
| 30/09/2000 | Tuffley Rovers | 2 | 1 | Almondsbury Town |
| 30/09/2000 | Yate Town (R) | 1 | 1 | North Leigh |
| 27/09/2000 | Highworth Town | 4 | 1 | Wootton Bassett Town (P) |
| 23/09/2000 | Almondsbury Town | 0 | 1 | Fairford Town |
| 23/09/2000 | Highworth Town | 3 | 0 | Cheltenham Saracens (P) |
| 23/09/2000 | Yate Town (R) | 0 | 4 | Wootton Bassett Town (P) |
| 20/09/2000 | Fairford Town | 1 | 0 | Cheltenham Saracens (P) |
| 20/09/2000 | Harrow Hill | 1 | 1 | Cirencester Academy |
| 20/09/2000 | North Leigh | 1 | 1 | Wantage Town |
| 19/09/2000 | Swindon Supermarine | 2 | 1 | Almondsbury Town |
| 19/09/2000 | Tuffley Rovers | 2 | 0 | Yate Town (R) |
| 19/09/2000 | Wootton Bassett Town (P) | 0 | 0 | Didcot Town |
| 16/09/2000 | Bicester Town | 0 | 3 | Yate Town (R) |
| 16/09/2000 | Cheltenham Saracens (P) | 2 | 2 | North Leigh |
| 16/09/2000 | Pegasus Juniors | 0 | 3 | Swindon Supermarine |
| 16/09/2000 | Wantage Town | 0 | 3 | Highworth Town |
| 16/09/2000 | Wootton Bassett Town (P) | 4 | 1 | Harrow Hill |
| 09/09/2000 | Cirencester Academy | 0 | 1 | Didcot Town |
| 09/09/2000 | Harrow Hill | 1 | 1 | Abingdon United |
| 09/09/2000 | Highworth Town | 5 | 0 | Milton United |
| 09/09/2000 | North Leigh | 2 | 5 | Tuffley Rovers |
| 09/09/2000 | Shortwood United | 4 | 2 | Wootton Bassett Town (P) |
| 09/09/2000 | Wantage Town | 1 | 4 | Pegasus Juniors |
| 09/09/2000 | Yate Town (R) | 0 | 1 | Swindon Supermarine |
| 06/09/2000 | Cheltenham Saracens (P) | 1 | 3 | Swindon Supermarine |
| 05/09/2000 | Milton United | 0 | 1 | Bicester Town |
| 02/09/2000 | Almondsbury Town | 3 | 2 | Bicester Town |
| 02/09/2000 | Harrow Hill | 1 | 1 | Wantage Town |
| 02/09/2000 | Milton United | 1 | 4 | Cheltenham Saracens (P) |
| 02/09/2000 | Pegasus Juniors | 2 | 3 | Fairford Town |
| 02/09/2000 | Swindon Supermarine | 4 | 2 | Cirencester Academy |
| 02/09/2000 | Wootton Bassett Town (P) | 0 | 4 | Highworth Town |
| 28/08/2000 | Almondsbury Town | 0 | 1 | Yate Town (R) |
| 28/08/2000 | Bicester Town | 0 | 0 | Brackley Town |
| 28/08/2000 | Carterton Town | 4 | 0 | North Leigh |
| 28/08/2000 | Cheltenham Saracens (P) | 1 | 2 | Wootton Bassett Town (P) |
| 28/08/2000 | Didcot Town | 2 | 0 | Abingdon United |
| 28/08/2000 | Fairford Town | 1 | 3 | Cirencester Academy |
| 28/08/2000 | Pegasus Juniors | 1 | 0 | Harrow Hill |
| 28/08/2000 | Shortwood United | 2 | 1 | Tuffley Rovers |
| 28/08/2000 | Swindon Supermarine | 1 | 1 | Highworth Town |
| 28/08/2000 | Wantage Town | 2 | 0 | Milton United |
| 26/08/2000 | Abingdon United | 1 | 0 | Fairford Town |
| 26/08/2000 | Bicester Town | 2 | 0 | Wantage Town |
| 26/08/2000 | Cheltenham Saracens (P) | 0 | 2 | Carterton Town |
| 26/08/2000 | Cirencester Academy | 4 | 1 | Harrow Hill |
| 26/08/2000 | Milton United | 0 | 2 | Brackley Town |
| 26/08/2000 | North Leigh | 0 | 2 | Didcot Town |
| 26/08/2000 | Pegasus Juniors | 3 | 3 | Shortwood United |
| 26/08/2000 | Tuffley Rovers | 0 | 3 | Swindon Supermarine |
| 26/08/2000 | Wootton Bassett Town (P) | 0 | 1 | Almondsbury Town |
| 23/08/2000 | Cirencester Academy | 2 | 0 | Pegasus Juniors |
| 23/08/2000 | Fairford Town | 1 | 0 | Swindon Supermarine |
| 23/08/2000 | Harrow Hill | 0 | 1 | Tuffley Rovers |
| 23/08/2000 | Highworth Town | 3 | 0 | Carterton Town |
| 23/08/2000 | North Leigh | 1 | 2 | Bicester Town |
| 23/08/2000 | Wootton Bassett Town (P) | 2 | 2 | Milton United |
| 22/08/2000 | Almondsbury Town | 0 | 1 | Cheltenham Saracens (P) |
| 22/08/2000 | Brackley Town | 2 | 1 | Abingdon United |
| 22/08/2000 | Wantage Town | 0 | 3 | Didcot Town |
| 22/08/2000 | Yate Town (R) | 2 | 2 | Shortwood United |
| 19/08/2000 | Abingdon United | 4 | 0 | Pegasus Juniors |
| 19/08/2000 | Brackley Town | 2 | 1 | Cirencester Academy |
| 19/08/2000 | Carterton Town | 7 | 2 | Yate Town (R) |
| 19/08/2000 | Didcot Town | 2 | 1 | Cheltenham Saracens (P) |
| 19/08/2000 | Fairford Town | 6 | 0 | Wootton Bassett Town (P) |
| 19/08/2000 | Harrow Hill | 2 | 2 | Bicester Town |
| 19/08/2000 | Milton United | 0 | 3 | Almondsbury Town |
| 19/08/2000 | Shortwood United | 2 | 3 | North Leigh |
| 19/08/2000 | Swindon Supermarine | 2 | 1 | Wantage Town |
| 19/08/2000 | Tuffley Rovers | 0 | 2 | Highworth Town |