| Northern Division One | ||||
| Date | Home | H | A | Away |
| 19/05/2001 | Consett | 2 | 0 | Newcastle Blue Star (P) |
| 19/05/2001 | Crook Town | 0 | 7 | Billingham Town |
| 19/05/2001 | Morpeth Town (-6) | 7 | 0 | Hebburn Town (P) |
| 19/05/2001 | Tow Law Town | 3 | 1 | Marske United |
| 18/05/2001 | Peterlee Newtown | 0 | 1 | Billingham Town |
| 16/05/2001 | Consett | 1 | 1 | Billingham Town |
| 15/05/2001 | Morpeth Town (-6) | 1 | 2 | West Auckland Town |
| 14/05/2001 | Crook Town | 0 | 1 | Marske United |
| 14/05/2001 | Tow Law Town | 2 | 0 | Billingham Town |
| 11/05/2001 | Billingham Town | 3 | 3 | Tow Law Town |
| 11/05/2001 | Crook Town | 0 | 4 | Morpeth Town (-6) |
| 11/05/2001 | Dunston Federation | 1 | 0 | Bedlington Terriers |
| 11/05/2001 | Newcastle Blue Star (P) | 0 | 2 | Marske United |
| 11/05/2001 | West Auckland Town | 3 | 1 | Whitley Bay (R) |
| 09/05/2001 | Billingham Town | 0 | 4 | West Auckland Town |
| 09/05/2001 | Consett | 1 | 1 | Bedlington Terriers |
| 09/05/2001 | Marske United | 3 | 0 | Easington Colliery |
| 07/05/2001 | Dunston Federation | 2 | 1 | Billingham Town |
| 07/05/2001 | Easington Colliery | 5 | 1 | Hebburn Town (P) |
| 07/05/2001 | Morpeth Town (-6) | 3 | 1 | Jarrow Roofing |
| 07/05/2001 | Newcastle Blue Star (P) | 2 | 5 | West Auckland Town |
| 07/05/2001 | Whitley Bay (R) | 1 | 3 | Tow Law Town |
| 05/05/2001 | Bedlington Terriers | 2 | 0 | Guisborough Town |
| 05/05/2001 | Brandon United (P) | 6 | 1 | Seaham Red Star |
| 05/05/2001 | Consett | 2 | 0 | Jarrow Roofing |
| 05/05/2001 | Crook Town | 1 | 1 | Easington Colliery |
| 05/05/2001 | Dunston Federation | 4 | 4 | Whitley Bay (R) |
| 05/05/2001 | Marske United | 4 | 2 | Billingham Town |
| 05/05/2001 | Morpeth Town (-6) | 1 | 2 | Billingham Synthonia |
| 05/05/2001 | Newcastle Blue Star (P) | 2 | 1 | Chester Le Street |
| 05/05/2001 | Tow Law Town | 4 | 0 | Hebburn Town (P) |
| 03/05/2001 | Morpeth Town (-6) | 3 | 0 | Peterlee Newtown |
| 02/05/2001 | Brandon United (P) | 1 | 1 | Bedlington Terriers |
| 02/05/2001 | Marske United | 2 | 0 | Whitley Bay (R) |
| 02/05/2001 | Seaham Red Star | 0 | 2 | Consett |
| 02/05/2001 | West Auckland Town | 2 | 5 | Billingham Town |
| 01/05/2001 | Easington Colliery | 0 | 0 | Newcastle Blue Star (P) |
| 30/04/2001 | Marske United | 2 | 1 | Chester Le Street |
| 30/04/2001 | Morpeth Town (-6) | 1 | 2 | Brandon United (P) |
| 30/04/2001 | Seaham Red Star | 1 | 0 | Billingham Town |
| 30/04/2001 | Tow Law Town | 2 | 1 | Bedlington Terriers |
| 28/04/2001 | Bedlington Terriers | 5 | 0 | Billingham Town |
| 28/04/2001 | Brandon United (P) | 1 | 0 | Billingham Synthonia |
| 28/04/2001 | Chester Le Street | 1 | 1 | Whitley Bay (R) |
| 28/04/2001 | Consett | 4 | 0 | Easington Colliery |
| 28/04/2001 | Guisborough Town | 1 | 2 | Tow Law Town |
| 28/04/2001 | Jarrow Roofing | 3 | 0 | Crook Town |
| 28/04/2001 | Marske United | 8 | 0 | Seaham Red Star |
| 28/04/2001 | Morpeth Town (-6) | 1 | 0 | Dunston Federation |
| 28/04/2001 | West Auckland Town | 2 | 3 | Peterlee Newtown |
| 26/04/2001 | Chester Le Street | 2 | 6 | Easington Colliery |
| 26/04/2001 | West Auckland Town | 1 | 2 | Newcastle Blue Star (P) |
| 26/04/2001 | Whitley Bay (R) | 0 | 2 | Bedlington Terriers |
| 25/04/2001 | Consett | 4 | 1 | Crook Town |
| 25/04/2001 | Hebburn Town (P) | 0 | 6 | Marske United |
| 25/04/2001 | Jarrow Roofing | 2 | 6 | Brandon United (P) |
| 24/04/2001 | Easington Colliery | 0 | 3 | Bedlington Terriers |
| 24/04/2001 | Whitley Bay (R) | 2 | 0 | Newcastle Blue Star (P) |
| 23/04/2001 | Crook Town | 2 | 3 | Seaham Red Star |
| 23/04/2001 | Guisborough Town | 2 | 2 | Peterlee Newtown |
| 23/04/2001 | Marske United | 0 | 0 | Billingham Synthonia |
| 21/04/2001 | Billingham Synthonia | 2 | 2 | Bedlington Terriers |
| 21/04/2001 | Brandon United (P) | 1 | 0 | Durham City |
| 21/04/2001 | Consett | 2 | 0 | Chester Le Street |
| 21/04/2001 | Crook Town | 1 | 4 | Whitley Bay (R) |
| 21/04/2001 | Guisborough Town | 1 | 2 | Easington Colliery |
| 21/04/2001 | Jarrow Roofing | 1 | 1 | Newcastle Blue Star (P) |
| 21/04/2001 | Marske United | 1 | 2 | Dunston Federation |
| 21/04/2001 | Morpeth Town (-6) | 2 | 2 | Billingham Town |
| 21/04/2001 | Seaham Red Star | 4 | 0 | Hebburn Town (P) |
| 21/04/2001 | West Auckland Town | 1 | 1 | Tow Law Town |
| 18/04/2001 | Bedlington Terriers | 3 | 0 | Peterlee Newtown |
| 18/04/2001 | Billingham Town | 1 | 0 | Crook Town |
| 18/04/2001 | Brandon United (P) | 1 | 0 | Consett |
| 18/04/2001 | Easington Colliery | 0 | 3 | Jarrow Roofing |
| 18/04/2001 | Hebburn Town (P) | 0 | 1 | Dunston Federation |
| 18/04/2001 | Morpeth Town (-6) | 4 | 0 | Seaham Red Star |
| 18/04/2001 | Newcastle Blue Star (P) | 2 | 3 | Tow Law Town |
| 16/04/2001 | Bedlington Terriers | 4 | 0 | Crook Town |
| 16/04/2001 | Brandon United (P) | 2 | 0 | Easington Colliery |
| 16/04/2001 | Chester Le Street | 2 | 3 | Billingham Town |
| 16/04/2001 | Dunston Federation | 2 | 1 | Newcastle Blue Star (P) |
| 16/04/2001 | Marske United | 2 | 0 | Guisborough Town |
| 16/04/2001 | Peterlee Newtown | 2 | 2 | Consett |
| 16/04/2001 | Tow Law Town | 0 | 0 | Whitley Bay (R) |
| 16/04/2001 | West Auckland Town | 2 | 0 | Seaham Red Star |
| 14/04/2001 | Billingham Town | 2 | 1 | Durham City |
| 14/04/2001 | Brandon United (P) | 3 | 2 | Morpeth Town (-6) |
| 14/04/2001 | Chester Le Street | 1 | 2 | Crook Town |
| 14/04/2001 | Easington Colliery | 1 | 1 | Consett |
| 14/04/2001 | Marske United | 0 | 2 | Bedlington Terriers |
| 14/04/2001 | Newcastle Blue Star (P) | 1 | 2 | Guisborough Town |
| 14/04/2001 | Peterlee Newtown | 2 | 2 | Billingham Synthonia |
| 14/04/2001 | Tow Law Town | 1 | 3 | Dunston Federation |
| 14/04/2001 | Whitley Bay (R) | 4 | 2 | Seaham Red Star |
| 13/04/2001 | Jarrow Roofing | 0 | 0 | Hebburn Town (P) |
| 12/04/2001 | Durham City | 1 | 0 | Whitley Bay (R) |
| 11/04/2001 | Bedlington Terriers | 2 | 0 | Chester Le Street |
| 11/04/2001 | Brandon United (P) | 3 | 2 | Dunston Federation |
| 11/04/2001 | West Auckland Town | 1 | 2 | Consett |
| 10/04/2001 | Billingham Synthonia | 1 | 2 | Durham City |
| 10/04/2001 | Easington Colliery | 0 | 1 | Marske United |
| 10/04/2001 | Guisborough Town | 2 | 0 | Billingham Town |
| 10/04/2001 | Tow Law Town | 5 | 3 | Newcastle Blue Star (P) |
| 10/04/2001 | Whitley Bay (R) | 2 | 2 | Crook Town |
| 07/04/2001 | Billingham Synthonia | 1 | 1 | Chester Le Street |
| 07/04/2001 | West Auckland Town | 1 | 2 | Bedlington Terriers |
| 05/04/2001 | Morpeth Town (-6) | 3 | 0 | Newcastle Blue Star (P) |
| 04/04/2001 | Hebburn Town (P) | 0 | 3 | Billingham Synthonia |
| 04/04/2001 | Peterlee Newtown | 0 | 1 | Dunston Federation |
| 03/04/2001 | Chester Le Street | 0 | 0 | Newcastle Blue Star (P) |
| 03/04/2001 | Easington Colliery | 0 | 3 | Tow Law Town |
| 31/03/2001 | Bedlington Terriers | 3 | 2 | Tow Law Town |
| 31/03/2001 | Billingham Town | 5 | 1 | Consett |
| 31/03/2001 | Brandon United (P) | 3 | 0 | Guisborough Town |
| 31/03/2001 | Chester Le Street | 1 | 1 | Dunston Federation |
| 31/03/2001 | Easington Colliery | 4 | 2 | Billingham Synthonia |
| 31/03/2001 | Marske United | 4 | 1 | Hebburn Town (P) |
| 31/03/2001 | Newcastle Blue Star (P) | 3 | 1 | Crook Town |
| 31/03/2001 | Peterlee Newtown | 1 | 1 | West Auckland Town |
| 31/03/2001 | Seaham Red Star | 0 | 2 | Durham City |
| 31/03/2001 | Whitley Bay (R) | 2 | 1 | Morpeth Town (-6) |
| 29/03/2001 | Seaham Red Star | 1 | 4 | Marske United |
| 28/03/2001 | Brandon United (P) | 4 | 2 | West Auckland Town |
| 28/03/2001 | Hebburn Town (P) | 1 | 5 | Peterlee Newtown |
| 27/03/2001 | Chester Le Street | 1 | 4 | Marske United |
| 27/03/2001 | Durham City | 1 | 2 | Billingham Town |
| 27/03/2001 | Guisborough Town | 2 | 0 | Billingham Synthonia |
| 27/03/2001 | Seaham Red Star | 1 | 2 | Easington Colliery |
| 24/03/2001 | Billingham Synthonia | 3 | 0 | Newcastle Blue Star (P) |
| 24/03/2001 | Consett | 3 | 3 | Brandon United (P) |
| 24/03/2001 | Easington Colliery | 2 | 3 | Dunston Federation |
| 24/03/2001 | Guisborough Town | 2 | 2 | Hebburn Town (P) |
| 24/03/2001 | Jarrow Roofing | 1 | 1 | Whitley Bay (R) |
| 24/03/2001 | Seaham Red Star | 2 | 3 | Morpeth Town (-6) |
| 24/03/2001 | Tow Law Town | 0 | 0 | Peterlee Newtown |
| 24/03/2001 | West Auckland Town | 0 | 3 | Chester Le Street |
| 21/03/2001 | Billingham Town | 2 | 1 | Easington Colliery |
| 21/03/2001 | Consett | 3 | 1 | Tow Law Town |
| 21/03/2001 | Peterlee Newtown | 4 | 1 | Seaham Red Star |
| 20/03/2001 | Billingham Synthonia | 1 | 1 | Marske United |
| 20/03/2001 | Dunston Federation | 2 | 0 | West Auckland Town |
| 20/03/2001 | Durham City | 1 | 1 | Guisborough Town |
| 20/03/2001 | Whitley Bay (R) | 0 | 0 | Hebburn Town (P) |
| 19/03/2001 | Jarrow Roofing | 4 | 3 | Bedlington Terriers |
| 17/03/2001 | Billingham Town | 1 | 0 | Chester Le Street |
| 17/03/2001 | Brandon United (P) | 3 | 1 | Crook Town |
| 17/03/2001 | Dunston Federation | 0 | 3 | Tow Law Town |
| 17/03/2001 | Durham City | 5 | 0 | Morpeth Town (-6) |
| 17/03/2001 | Easington Colliery | 0 | 1 | West Auckland Town |
| 17/03/2001 | Hebburn Town (P) | 1 | 0 | Consett |
| 17/03/2001 | Newcastle Blue Star (P) | 3 | 2 | Billingham Synthonia |
| 17/03/2001 | Peterlee Newtown | 1 | 0 | Marske United |
| 17/03/2001 | Seaham Red Star | 0 | 1 | Jarrow Roofing |
| 17/03/2001 | Whitley Bay (R) | 1 | 0 | Guisborough Town |
| 14/03/2001 | Billingham Town | 1 | 2 | Peterlee Newtown |
| 14/03/2001 | Crook Town | 1 | 2 | Chester Le Street |
| 14/03/2001 | Guisborough Town | 0 | 2 | Marske United |
| 14/03/2001 | Jarrow Roofing | 1 | 1 | Easington Colliery |
| 13/03/2001 | Newcastle Blue Star (P) | 0 | 5 | Dunston Federation |
| 13/03/2001 | Whitley Bay (R) | 1 | 1 | Billingham Synthonia |
| 10/03/2001 | Billingham Synthonia | 1 | 1 | Brandon United (P) |
| 10/03/2001 | Chester Le Street | 3 | 4 | West Auckland Town |
| 10/03/2001 | Consett | 1 | 2 | Whitley Bay (R) |
| 10/03/2001 | Crook Town | 2 | 3 | Hebburn Town (P) |
| 10/03/2001 | Guisborough Town | 0 | 1 | Seaham Red Star |
| 10/03/2001 | Jarrow Roofing | 1 | 2 | Durham City |
| 10/03/2001 | Tow Law Town | 4 | 2 | Easington Colliery |
| 07/03/2001 | Easington Colliery | 2 | 3 | Peterlee Newtown |
| 07/03/2001 | Hebburn Town (P) | 0 | 7 | Whitley Bay (R) |
| 06/03/2001 | Chester Le Street | 2 | 0 | Seaham Red Star |
| 06/03/2001 | Dunston Federation | 2 | 1 | Durham City |
| 24/02/2001 | Bedlington Terriers | 5 | 0 | Easington Colliery |
| 24/02/2001 | Billingham Synthonia | 3 | 2 | Whitley Bay (R) |
| 24/02/2001 | Consett | 0 | 4 | Durham City |
| 24/02/2001 | Dunston Federation | 1 | 3 | Brandon United (P) |
| 24/02/2001 | Guisborough Town | 1 | 1 | Morpeth Town (-6) |
| 24/02/2001 | Hebburn Town (P) | 2 | 1 | Jarrow Roofing |
| 24/02/2001 | Marske United | 2 | 4 | West Auckland Town |
| 24/02/2001 | Peterlee Newtown | 3 | 1 | Chester Le Street |
| 21/02/2001 | Bedlington Terriers | 3 | 0 | Hebburn Town (P) |
| 21/02/2001 | Billingham Town | 0 | 0 | Jarrow Roofing |
| 20/02/2001 | Dunston Federation | 1 | 0 | Chester Le Street |
| 20/02/2001 | Newcastle Blue Star (P) | 2 | 1 | Morpeth Town (-6) |
| 20/02/2001 | Tow Law Town | 1 | 3 | West Auckland Town |
| 17/02/2001 | Billingham Town | 0 | 1 | Marske United |
| 17/02/2001 | Brandon United (P) | 2 | 0 | Tow Law Town |
| 17/02/2001 | Durham City | 8 | 2 | Crook Town |
| 17/02/2001 | Hebburn Town (P) | 1 | 3 | West Auckland Town |
| 17/02/2001 | Jarrow Roofing | 2 | 1 | Guisborough Town |
| 17/02/2001 | Morpeth Town (-6) | 1 | 3 | Consett |
| 17/02/2001 | Newcastle Blue Star (P) | 0 | 1 | Bedlington Terriers |
| 17/02/2001 | Peterlee Newtown | 2 | 0 | Easington Colliery |
| 17/02/2001 | Seaham Red Star | 3 | 2 | Billingham Synthonia |
| 17/02/2001 | Whitley Bay (R) | 1 | 5 | Dunston Federation |
| 14/02/2001 | Bedlington Terriers | 2 | 0 | Marske United |
| 13/02/2001 | Chester Le Street | 1 | 0 | Guisborough Town |
| 13/02/2001 | Dunston Federation | 3 | 2 | Easington Colliery |
| 13/02/2001 | Whitley Bay (R) | 0 | 3 | Jarrow Roofing |
| 10/02/2001 | Peterlee Newtown | 2 | 0 | Newcastle Blue Star (P) |
| 03/02/2001 | Durham City | 4 | 2 | Dunston Federation |
| 03/02/2001 | Guisborough Town | 1 | 2 | Consett |
| 03/02/2001 | Seaham Red Star | 2 | 0 | West Auckland Town |
| 31/01/2001 | Jarrow Roofing | 1 | 1 | Dunston Federation |
| 30/01/2001 | Chester Le Street | 4 | 0 | Tow Law Town |
| 27/01/2001 | Billingham Synthonia | 0 | 4 | Jarrow Roofing |
| 27/01/2001 | Crook Town | 0 | 1 | Guisborough Town |
| 27/01/2001 | Dunston Federation | 3 | 1 | Morpeth Town (-6) |
| 27/01/2001 | Newcastle Blue Star (P) | 1 | 0 | Easington Colliery |
| 27/01/2001 | Peterlee Newtown | 2 | 0 | Brandon United (P) |
| 27/01/2001 | Tow Law Town | 2 | 2 | Seaham Red Star |
| 27/01/2001 | West Auckland Town | 1 | 2 | Durham City |
| 24/01/2001 | Hebburn Town (P) | 1 | 1 | Billingham Town |
| 20/01/2001 | Durham City | 0 | 1 | Tow Law Town |
| 20/01/2001 | Whitley Bay (R) | 2 | 1 | Brandon United (P) |
| 17/01/2001 | Crook Town | 0 | 2 | West Auckland Town |
| 17/01/2001 | Peterlee Newtown | 4 | 2 | Tow Law Town |
| 13/01/2001 | Bedlington Terriers | 8 | 2 | Seaham Red Star |
| 13/01/2001 | Billingham Synthonia | 3 | 0 | Consett |
| 13/01/2001 | Dunston Federation | 13 | 0 | Crook Town |
| 13/01/2001 | Easington Colliery | 1 | 1 | Brandon United (P) |
| 13/01/2001 | Hebburn Town (P) | 0 | 3 | Chester Le Street |
| 13/01/2001 | Marske United | 1 | 0 | Durham City |
| 13/01/2001 | Newcastle Blue Star (P) | 0 | 5 | Billingham Town |
| 13/01/2001 | Peterlee Newtown | 2 | 4 | Whitley Bay (R) |
| 13/01/2001 | Tow Law Town | 5 | 1 | Morpeth Town (-6) |
| 13/01/2001 | West Auckland Town | 1 | 1 | Jarrow Roofing |
| 10/01/2001 | Bedlington Terriers | 2 | 3 | Newcastle Blue Star (P) |
| 10/01/2001 | Billingham Town | 1 | 1 | Dunston Federation |
| 10/01/2001 | Hebburn Town (P) | 2 | 4 | Crook Town |
| 10/01/2001 | Jarrow Roofing | 2 | 4 | Seaham Red Star |
| 09/01/2001 | Durham City | 1 | 2 | Consett |
| 09/01/2001 | Morpeth Town (-6) | 0 | 2 | Easington Colliery |
| 06/01/2001 | Billingham Town | 0 | 0 | Brandon United (P) |
| 06/01/2001 | Consett | 0 | 2 | Dunston Federation |
| 06/01/2001 | Crook Town | 1 | 2 | Billingham Synthonia |
| 06/01/2001 | Guisborough Town | 4 | 0 | West Auckland Town |
| 06/01/2001 | Hebburn Town (P) | 1 | 1 | Easington Colliery |
| 06/01/2001 | Jarrow Roofing | 3 | 3 | Tow Law Town |
| 06/01/2001 | Morpeth Town (-6) | 0 | 2 | Marske United |
| 06/01/2001 | Seaham Red Star | 1 | 4 | Peterlee Newtown |
| 06/01/2001 | Whitley Bay (R) | 1 | 3 | Chester Le Street |
| 05/01/2001 | Durham City | 1 | 0 | Bedlington Terriers |
| 03/01/2001 | Bedlington Terriers | 2 | 0 | Morpeth Town (-6) |
| 26/12/2000 | Billingham Town | 1 | 2 | Billingham Synthonia |
| 26/12/2000 | Durham City | 2 | 1 | Chester Le Street |
| 23/12/2000 | Billingham Town | 1 | 0 | Whitley Bay (R) |
| 23/12/2000 | Chester Le Street | 3 | 2 | Morpeth Town (-6) |
| 23/12/2000 | Dunston Federation | 3 | 1 | Guisborough Town |
| 23/12/2000 | Easington Colliery | 2 | 5 | Durham City |
| 23/12/2000 | Hebburn Town (P) | 0 | 1 | Brandon United (P) |
| 23/12/2000 | Marske United | 4 | 1 | Consett |
| 23/12/2000 | Newcastle Blue Star (P) | 2 | 2 | Seaham Red Star |
| 23/12/2000 | Peterlee Newtown | 3 | 2 | Jarrow Roofing |
| 23/12/2000 | Tow Law Town | 8 | 3 | Crook Town |
| 23/12/2000 | West Auckland Town | 0 | 0 | Billingham Synthonia |
| 20/12/2000 | Bedlington Terriers | 3 | 1 | Brandon United (P) |
| 16/12/2000 | Billingham Synthonia | 0 | 1 | Tow Law Town |
| 16/12/2000 | Hebburn Town (P) | 2 | 2 | Newcastle Blue Star (P) |
| 16/12/2000 | Jarrow Roofing | 3 | 1 | Chester Le Street |
| 13/12/2000 | Chester Le Street | 1 | 2 | Bedlington Terriers |
| 13/12/2000 | Seaham Red Star | 3 | 0 | Crook Town |
| 09/12/2000 | Durham City | 3 | 1 | West Auckland Town |
| 09/12/2000 | Guisborough Town | 0 | 3 | Chester Le Street |
| 09/12/2000 | Seaham Red Star | 0 | 9 | Brandon United (P) |
| 05/12/2000 | Durham City | 5 | 0 | Seaham Red Star |
| 02/12/2000 | Bedlington Terriers | 0 | 2 | Billingham Synthonia |
| 02/12/2000 | Billingham Town | 5 | 2 | Morpeth Town (-6) |
| 02/12/2000 | Chester Le Street | 0 | 1 | Consett |
| 02/12/2000 | Dunston Federation | 4 | 2 | Marske United |
| 02/12/2000 | Easington Colliery | 2 | 0 | Guisborough Town |
| 02/12/2000 | Hebburn Town (P) | 0 | 2 | Seaham Red Star |
| 02/12/2000 | Newcastle Blue Star (P) | 2 | 1 | Jarrow Roofing |
| 02/12/2000 | Peterlee Newtown | 4 | 1 | Crook Town |
| 02/12/2000 | West Auckland Town | 1 | 2 | Brandon United (P) |
| 28/11/2000 | Billingham Synthonia | 10 | 1 | Crook Town |
| 25/11/2000 | Billingham Synthonia | 4 | 2 | Peterlee Newtown |
| 25/11/2000 | Durham City | 5 | 0 | Hebburn Town (P) |
| 25/11/2000 | Guisborough Town | 2 | 0 | Newcastle Blue Star (P) |
| 25/11/2000 | Jarrow Roofing | 0 | 1 | Billingham Town |
| 25/11/2000 | Seaham Red Star | 0 | 2 | Whitley Bay (R) |
| 25/11/2000 | West Auckland Town | 0 | 0 | Marske United |
| 18/11/2000 | Bedlington Terriers | 0 | 1 | West Auckland Town |
| 18/11/2000 | Billingham Town | 3 | 2 | Guisborough Town |
| 18/11/2000 | Brandon United (P) | 2 | 3 | Jarrow Roofing |
| 18/11/2000 | Chester Le Street | 1 | 2 | Billingham Synthonia |
| 18/11/2000 | Dunston Federation | 7 | 0 | Seaham Red Star |
| 18/11/2000 | Easington Colliery | 6 | 0 | Crook Town |
| 18/11/2000 | Hebburn Town (P) | 2 | 3 | Morpeth Town (-6) |
| 18/11/2000 | Marske United | 1 | 0 | Tow Law Town |
| 18/11/2000 | Newcastle Blue Star (P) | 3 | 1 | Consett |
| 18/11/2000 | Whitley Bay (R) | 1 | 2 | Durham City |
| 14/11/2000 | Billingham Synthonia | 3 | 2 | Easington Colliery |
| 14/11/2000 | Morpeth Town (-6) | 1 | 2 | Whitley Bay (R) |
| 11/11/2000 | Brandon United (P) | 0 | 2 | Chester Le Street |
| 11/11/2000 | Hebburn Town (P) | 2 | 4 | Guisborough Town |
| 11/11/2000 | Peterlee Newtown | 4 | 1 | Durham City |
| 04/11/2000 | Bedlington Terriers | 4 | 0 | Dunston Federation |
| 04/11/2000 | Billingham Synthonia | 2 | 0 | Billingham Town |
| 04/11/2000 | Consett | 4 | 0 | Hebburn Town (P) |
| 04/11/2000 | Crook Town | 0 | 6 | Brandon United (P) |
| 04/11/2000 | Guisborough Town | 2 | 1 | Whitley Bay (R) |
| 04/11/2000 | Marske United | 1 | 1 | Peterlee Newtown |
| 04/11/2000 | Morpeth Town (-6) | 1 | 0 | Durham City |
| 04/11/2000 | Tow Law Town | 1 | 2 | Chester Le Street |
| 04/11/2000 | West Auckland Town | 2 | 0 | Easington Colliery |
| 01/11/2000 | Peterlee Newtown | 0 | 6 | Bedlington Terriers |
| 01/11/2000 | Seaham Red Star | 1 | 2 | Guisborough Town |
| 31/10/2000 | Durham City | 3 | 1 | Jarrow Roofing |
| 28/10/2000 | Billingham Synthonia | 3 | 2 | Hebburn Town (P) |
| 28/10/2000 | Brandon United (P) | 3 | 2 | Newcastle Blue Star (P) |
| 28/10/2000 | Chester Le Street | 0 | 1 | Peterlee Newtown |
| 28/10/2000 | Consett | 4 | 2 | Seaham Red Star |
| 28/10/2000 | Guisborough Town | 0 | 3 | Durham City |
| 28/10/2000 | Marske United | 4 | 1 | Jarrow Roofing |
| 28/10/2000 | West Auckland Town | 3 | 3 | Crook Town |
| 25/10/2000 | Jarrow Roofing | 2 | 2 | Morpeth Town (-6) |
| 21/10/2000 | Consett | 0 | 2 | Peterlee Newtown |
| 21/10/2000 | Durham City | 6 | 2 | Newcastle Blue Star (P) |
| 21/10/2000 | Hebburn Town (P) | 1 | 5 | Bedlington Terriers |
| 21/10/2000 | Morpeth Town (-6) | 1 | 1 | Guisborough Town |
| 18/10/2000 | Hebburn Town (P) | 0 | 5 | Durham City |
| 17/10/2000 | Billingham Synthonia | 2 | 2 | Dunston Federation |
| 17/10/2000 | Tow Law Town | 1 | 3 | Guisborough Town |
| 14/10/2000 | Billingham Synthonia | 3 | 1 | Seaham Red Star |
| 14/10/2000 | Consett | 0 | 0 | Morpeth Town (-6) |
| 14/10/2000 | Crook Town | 0 | 5 | Durham City |
| 14/10/2000 | Dunston Federation | 2 | 1 | Peterlee Newtown |
| 14/10/2000 | Guisborough Town | 3 | 0 | Jarrow Roofing |
| 14/10/2000 | Marske United | 2 | 3 | Newcastle Blue Star (P) |
| 14/10/2000 | Tow Law Town | 0 | 1 | Brandon United (P) |
| 14/10/2000 | West Auckland Town | 1 | 0 | Hebburn Town (P) |
| 11/10/2000 | Jarrow Roofing | 2 | 2 | Billingham Synthonia |
| 10/10/2000 | Guisborough Town | 2 | 0 | Crook Town |
| 10/10/2000 | Whitley Bay (R) | 1 | 1 | Marske United |
| 07/10/2000 | Brandon United (P) | 2 | 1 | Marske United |
| 07/10/2000 | Easington Colliery | 4 | 0 | Chester Le Street |
| 07/10/2000 | Jarrow Roofing | 1 | 1 | Consett |
| 07/10/2000 | Morpeth Town (-6) | 2 | 0 | Crook Town |
| 07/10/2000 | Whitley Bay (R) | 1 | 1 | West Auckland Town |
| 06/10/2000 | Billingham Town | 1 | 5 | Bedlington Terriers |
| 06/10/2000 | Durham City | 3 | 1 | Billingham Synthonia |
| 06/10/2000 | Hebburn Town (P) | 1 | 2 | Tow Law Town |
| 06/10/2000 | Newcastle Blue Star (P) | 0 | 0 | Peterlee Newtown |
| 06/10/2000 | Seaham Red Star | 3 | 2 | Dunston Federation |
| 04/10/2000 | Consett | 3 | 1 | Billingham Synthonia |
| 03/10/2000 | Guisborough Town | 0 | 0 | Dunston Federation |
| 03/10/2000 | Morpeth Town (-6) | 1 | 2 | Tow Law Town |
| 03/10/2000 | Newcastle Blue Star (P) | 4 | 0 | Brandon United (P) |
| 03/10/2000 | Whitley Bay (R) | 1 | 2 | Peterlee Newtown |
| 30/09/2000 | Billingham Synthonia | 2 | 2 | Morpeth Town (-6) |
| 30/09/2000 | Brandon United (P) | 2 | 2 | Peterlee Newtown |
| 30/09/2000 | Consett | 1 | 1 | Guisborough Town |
| 30/09/2000 | Crook Town | 0 | 4 | Jarrow Roofing |
| 30/09/2000 | Dunston Federation | 0 | 0 | Hebburn Town (P) |
| 26/09/2000 | Guisborough Town | 4 | 1 | Brandon United (P) |
| 23/09/2000 | Crook Town | 1 | 9 | Bedlington Terriers |
| 23/09/2000 | Seaham Red Star | 3 | 2 | Tow Law Town |
| 23/09/2000 | Whitley Bay (R) | 3 | 2 | Consett |
| 20/09/2000 | Bedlington Terriers | 1 | 1 | Whitley Bay (R) |
| 20/09/2000 | Crook Town | 2 | 2 | Newcastle Blue Star (P) |
| 20/09/2000 | Peterlee Newtown | 1 | 0 | Hebburn Town (P) |
| 19/09/2000 | Dunston Federation | 3 | 2 | Jarrow Roofing |
| 19/09/2000 | Easington Colliery | 1 | 6 | Billingham Town |
| 19/09/2000 | Tow Law Town | 3 | 3 | Durham City |
| 19/09/2000 | West Auckland Town | 3 | 2 | Morpeth Town (-6) |
| 16/09/2000 | Billingham Synthonia | 3 | 2 | Guisborough Town |
| 16/09/2000 | Chester Le Street | 2 | 3 | Brandon United (P) |
| 16/09/2000 | Crook Town | 0 | 2 | Peterlee Newtown |
| 16/09/2000 | Tow Law Town | 5 | 0 | Jarrow Roofing |
| 12/09/2000 | Durham City | 2 | 2 | Brandon United (P) |
| 09/09/2000 | Billingham Town | 4 | 1 | Newcastle Blue Star (P) |
| 09/09/2000 | Chester Le Street | 3 | 0 | Hebburn Town (P) |
| 09/09/2000 | Durham City | 1 | 1 | Marske United |
| 09/09/2000 | Easington Colliery | 1 | 4 | Whitley Bay (R) |
| 09/09/2000 | Jarrow Roofing | 3 | 1 | West Auckland Town |
| 09/09/2000 | Seaham Red Star | 0 | 2 | Bedlington Terriers |
| 09/09/2000 | Tow Law Town | 3 | 0 | Consett |
| 06/09/2000 | Bedlington Terriers | 2 | 1 | Durham City |
| 05/09/2000 | Dunston Federation | 2 | 1 | Consett |
| 05/09/2000 | Marske United | 3 | 0 | Morpeth Town (-6) |
| 05/09/2000 | West Auckland Town | 4 | 1 | Guisborough Town |
| 28/08/2000 | Brandon United (P) | 0 | 1 | Billingham Town |
| 28/08/2000 | Consett | 3 | 1 | West Auckland Town |
| 28/08/2000 | Crook Town | 0 | 2 | Dunston Federation |
| 28/08/2000 | Durham City | 1 | 1 | Peterlee Newtown |
| 28/08/2000 | Jarrow Roofing | 0 | 3 | Marske United |
| 28/08/2000 | Morpeth Town (-6) | 0 | 3 | Bedlington Terriers |
| 28/08/2000 | Newcastle Blue Star (P) | 3 | 2 | Hebburn Town (P) |
| 28/08/2000 | Seaham Red Star | 4 | 2 | Chester Le Street |
| 28/08/2000 | Whitley Bay (R) | 5 | 0 | Easington Colliery |
| 26/08/2000 | Bedlington Terriers | 3 | 0 | Jarrow Roofing |
| 26/08/2000 | Billingham Town | 0 | 1 | Hebburn Town (P) |
| 26/08/2000 | Chester Le Street | 0 | 1 | Durham City |
| 26/08/2000 | Crook Town | 1 | 3 | Consett |
| 26/08/2000 | Dunston Federation | 2 | 1 | Billingham Synthonia |
| 26/08/2000 | Easington Colliery | 3 | 2 | Seaham Red Star |
| 26/08/2000 | Marske United | 0 | 0 | Brandon United (P) |
| 26/08/2000 | Newcastle Blue Star (P) | 0 | 2 | Whitley Bay (R) |
| 26/08/2000 | Peterlee Newtown | 2 | 1 | Morpeth Town (-6) |
| 23/08/2000 | Brandon United (P) | 3 | 4 | Hebburn Town (P) |
| 23/08/2000 | Consett | 0 | 1 | Marske United |
| 23/08/2000 | Crook Town | 0 | 6 | Tow Law Town |
| 23/08/2000 | Jarrow Roofing | 2 | 0 | Peterlee Newtown |
| 23/08/2000 | Seaham Red Star | 3 | 1 | Newcastle Blue Star (P) |
| 22/08/2000 | Billingham Synthonia | 4 | 0 | West Auckland Town |
| 22/08/2000 | Durham City | 2 | 0 | Easington Colliery |
| 22/08/2000 | Guisborough Town | 1 | 1 | Bedlington Terriers |
| 22/08/2000 | Morpeth Town (-6) | 0 | 6 | Chester Le Street |
| 22/08/2000 | Whitley Bay (R) | 2 | 4 | Billingham Town |
| 19/08/2000 | Bedlington Terriers | 3 | 0 | Consett |
| 19/08/2000 | Billingham Town | 1 | 2 | Seaham Red Star |
| 19/08/2000 | Brandon United (P) | 1 | 0 | Whitley Bay (R) |
| 19/08/2000 | Chester Le Street | 1 | 1 | Jarrow Roofing |
| 19/08/2000 | Easington Colliery | 1 | 2 | Morpeth Town (-6) |
| 19/08/2000 | Marske United | 4 | 0 | Crook Town |
| 19/08/2000 | Newcastle Blue Star (P) | 0 | 0 | Durham City |
| 19/08/2000 | Peterlee Newtown | 3 | 1 | Guisborough Town |
| 19/08/2000 | Tow Law Town | 0 | 3 | Billingham Synthonia |
| 19/08/2000 | West Auckland Town | 0 | 1 | Dunston Federation |