| Western Premier | ||||
| Date | Home | H | A | Away |
| 20/05/2001 | Bishop Sutton | 3 | 1 | Elmore |
| 19/05/2001 | Bishop Sutton | 0 | 4 | Devizes Town (P) |
| 19/05/2001 | Bridport | 0 | 2 | Paulton Rovers |
| 19/05/2001 | Brislington | 3 | 0 | Dawlish Town |
| 19/05/2001 | Elmore | 1 | 4 | Chippenham Town |
| 17/05/2001 | Bridgwater Town (-3) | 1 | 0 | Welton Rovers (P) |
| 17/05/2001 | Brislington | 1 | 1 | Odd Down |
| 16/05/2001 | Bishop Sutton | 1 | 1 | Dawlish Town |
| 16/05/2001 | Taunton Town | 3 | 1 | Yeovil Town Reserves |
| 15/05/2001 | Bridgwater Town (-3) | 0 | 0 | Devizes Town (P) |
| 15/05/2001 | Brislington | 1 | 0 | Bridport |
| 15/05/2001 | Elmore | 3 | 0 | Bideford |
| 15/05/2001 | Odd Down | 0 | 0 | Melksham Town |
| 15/05/2001 | Paulton Rovers | 1 | 2 | Chippenham Town |
| 14/05/2001 | Bishop Sutton | 5 | 1 | Westbury United |
| 14/05/2001 | Yeovil Town Reserves | 2 | 1 | Dawlish Town |
| 12/05/2001 | Barnstaple Town | 2 | 1 | Melksham Town |
| 12/05/2001 | Devizes Town (P) | 1 | 1 | Dawlish Town |
| 10/05/2001 | Bristol Manor Farm | 0 | 2 | Yeovil Town Reserves |
| 10/05/2001 | Taunton Town | 3 | 1 | Bideford |
| 09/05/2001 | Backwell United | 1 | 1 | Melksham Town |
| 09/05/2001 | Devizes Town (P) | 5 | 0 | Bishop Sutton |
| 09/05/2001 | Westbury United | 1 | 5 | Chippenham Town |
| 08/05/2001 | Brislington | 3 | 0 | Bridgwater Town (-3) |
| 07/05/2001 | Bridgwater Town (-3) | 3 | 0 | Elmore |
| 07/05/2001 | Bridport | 1 | 1 | Bideford |
| 07/05/2001 | Dawlish Town | 1 | 6 | Chippenham Town |
| 07/05/2001 | Devizes Town (P) | 6 | 0 | Barnstaple Town |
| 07/05/2001 | Welton Rovers (P) | 0 | 0 | Melksham Town |
| 07/05/2001 | Yeovil Town Reserves | 5 | 1 | Bishop Sutton |
| 05/05/2001 | Barnstaple Town | 3 | 0 | Westbury United |
| 05/05/2001 | Bridgwater Town (-3) | 1 | 0 | Odd Down |
| 05/05/2001 | Bridport | 1 | 3 | Backwell United |
| 05/05/2001 | Bristol Manor Farm | 3 | 2 | Devizes Town (P) |
| 05/05/2001 | Dawlish Town | 1 | 2 | Brislington |
| 05/05/2001 | Melksham Town | 3 | 0 | Elmore |
| 05/05/2001 | Minehead Town (-3) | 0 | 3 | Bishop Sutton |
| 05/05/2001 | Paulton Rovers | 1 | 1 | Bideford |
| 03/05/2001 | Bridgwater Town (-3) | 1 | 5 | Chippenham Town |
| 02/05/2001 | Bishop Sutton | 0 | 2 | Melksham Town |
| 02/05/2001 | Paulton Rovers | 2 | 0 | Welton Rovers (P) |
| 02/05/2001 | Westbury United | 0 | 3 | Brislington |
| 01/05/2001 | Bridgwater Town (-3) | 1 | 1 | Dawlish Town |
| 01/05/2001 | Bristol Manor Farm | 1 | 4 | Chippenham Town |
| 01/05/2001 | Elmore | 2 | 2 | Bridport |
| 01/05/2001 | Odd Down | 0 | 1 | Devizes Town (P) |
| 30/04/2001 | Westbury United | 1 | 2 | Bishop Sutton |
| 30/04/2001 | Yeovil Town Reserves | 1 | 1 | Paulton Rovers |
| 29/04/2001 | Melksham Town | 3 | 0 | Minehead Town (-3) |
| 28/04/2001 | Backwell United | 2 | 0 | Dawlish Town |
| 28/04/2001 | Barnstaple Town | 0 | 2 | Bishop Sutton |
| 28/04/2001 | Bridport | 1 | 0 | Brislington |
| 28/04/2001 | Chippenham Town | 3 | 0 | Elmore |
| 28/04/2001 | Melksham Town | 1 | 0 | Bridgwater Town (-3) |
| 28/04/2001 | Minehead Town (-3) | 1 | 4 | Devizes Town (P) |
| 28/04/2001 | Paulton Rovers | 2 | 1 | Bristol Manor Farm |
| 28/04/2001 | Welton Rovers (P) | 1 | 3 | Taunton Town |
| 28/04/2001 | Westbury United | 1 | 2 | Bideford |
| 28/04/2001 | Yeovil Town Reserves | 2 | 0 | Odd Down |
| 26/04/2001 | Bishop Sutton | 2 | 6 | Welton Rovers (P) |
| 26/04/2001 | Bridgwater Town (-3) | 1 | 2 | Backwell United |
| 26/04/2001 | Devizes Town (P) | 7 | 0 | Minehead Town (-3) |
| 26/04/2001 | Paulton Rovers | 1 | 2 | Elmore |
| 25/04/2001 | Chippenham Town | 5 | 0 | Bridport |
| 24/04/2001 | Brislington | 3 | 3 | Yeovil Town Reserves |
| 24/04/2001 | Melksham Town | 2 | 0 | Westbury United |
| 24/04/2001 | Minehead Town (-3) | 0 | 6 | Paulton Rovers |
| 24/04/2001 | Odd Down | 3 | 0 | Bishop Sutton |
| 24/04/2001 | Taunton Town | 1 | 1 | Backwell United |
| 24/04/2001 | Welton Rovers (P) | 2 | 3 | Bridgwater Town (-3) |
| 22/04/2001 | Melksham Town | 1 | 0 | Barnstaple Town |
| 21/04/2001 | Backwell United | 0 | 2 | Brislington |
| 21/04/2001 | Bideford | 2 | 2 | Devizes Town (P) |
| 21/04/2001 | Bridgwater Town (-3) | 1 | 1 | Bishop Sutton |
| 21/04/2001 | Melksham Town | 0 | 1 | Dawlish Town |
| 21/04/2001 | Minehead Town (-3) | 1 | 5 | Bridport |
| 21/04/2001 | Odd Down | 1 | 0 | Barnstaple Town |
| 21/04/2001 | Paulton Rovers | 2 | 1 | Yeovil Town Reserves |
| 21/04/2001 | Taunton Town | 1 | 1 | Chippenham Town |
| 21/04/2001 | Welton Rovers (P) | 2 | 3 | Elmore |
| 19/04/2001 | Odd Down | 0 | 0 | Bridgwater Town (-3) |
| 19/04/2001 | Westbury United | 0 | 1 | Backwell United |
| 18/04/2001 | Paulton Rovers | 3 | 2 | Bishop Sutton |
| 18/04/2001 | Yeovil Town Reserves | 5 | 0 | Welton Rovers (P) |
| 17/04/2001 | Westbury United | 2 | 4 | Elmore |
| 16/04/2001 | Bristol Manor Farm | 1 | 1 | Barnstaple Town |
| 16/04/2001 | Chippenham Town | 5 | 1 | Devizes Town (P) |
| 16/04/2001 | Melksham Town | 2 | 3 | Paulton Rovers |
| 16/04/2001 | Taunton Town | 1 | 0 | Bridgwater Town (-3) |
| 16/04/2001 | Yeovil Town Reserves | 0 | 3 | Bideford |
| 14/04/2001 | Backwell United | 5 | 0 | Minehead Town (-3) |
| 14/04/2001 | Bridport | 0 | 1 | Yeovil Town Reserves |
| 14/04/2001 | Brislington | 2 | 1 | Elmore |
| 14/04/2001 | Chippenham Town | 4 | 0 | Westbury United |
| 14/04/2001 | Odd Down | 1 | 0 | Dawlish Town |
| 13/04/2001 | Bideford | 2 | 2 | Barnstaple Town |
| 13/04/2001 | Bishop Sutton | 2 | 1 | Bristol Manor Farm |
| 13/04/2001 | Dawlish Town | 2 | 0 | Elmore |
| 13/04/2001 | Melksham Town | 0 | 3 | Chippenham Town |
| 13/04/2001 | Welton Rovers (P) | 4 | 0 | Paulton Rovers |
| 13/04/2001 | Westbury United | 3 | 2 | Devizes Town (P) |
| 10/04/2001 | Backwell United | 3 | 0 | Barnstaple Town |
| 10/04/2001 | Bridgwater Town (-3) | 2 | 2 | Paulton Rovers |
| 10/04/2001 | Taunton Town | 2 | 0 | Welton Rovers (P) |
| 09/04/2001 | Yeovil Town Reserves | 3 | 1 | Bristol Manor Farm |
| 07/04/2001 | Barnstaple Town | 1 | 0 | Backwell United |
| 07/04/2001 | Bideford | 3 | 3 | Melksham Town |
| 07/04/2001 | Bristol Manor Farm | 0 | 1 | Taunton Town |
| 07/04/2001 | Chippenham Town | 2 | 0 | Dawlish Town |
| 07/04/2001 | Devizes Town (P) | 0 | 4 | Elmore |
| 07/04/2001 | Minehead Town (-3) | 4 | 1 | Westbury United |
| 07/04/2001 | Paulton Rovers | 5 | 0 | Bridport |
| 07/04/2001 | Yeovil Town Reserves | 1 | 1 | Bridgwater Town (-3) |
| 04/04/2001 | Westbury United | 1 | 6 | Paulton Rovers |
| 03/04/2001 | Brislington | 0 | 3 | Chippenham Town |
| 03/04/2001 | Minehead Town (-3) | 0 | 5 | Bideford |
| 03/04/2001 | Odd Down | 1 | 4 | Welton Rovers (P) |
| 02/04/2001 | Taunton Town | 2 | 1 | Bishop Sutton |
| 31/03/2001 | Bideford | 0 | 0 | Paulton Rovers |
| 31/03/2001 | Bristol Manor Farm | 1 | 1 | Bridport |
| 31/03/2001 | Chippenham Town | 8 | 0 | Minehead Town (-3) |
| 31/03/2001 | Dawlish Town | 2 | 0 | Bridgwater Town (-3) |
| 31/03/2001 | Devizes Town (P) | 1 | 2 | Taunton Town |
| 31/03/2001 | Elmore | 1 | 3 | Bishop Sutton |
| 31/03/2001 | Westbury United | 0 | 0 | Barnstaple Town |
| 31/03/2001 | Yeovil Town Reserves | 4 | 0 | Melksham Town |
| 26/03/2001 | Yeovil Town Reserves | 1 | 2 | Brislington |
| 24/03/2001 | Backwell United | 2 | 0 | Odd Down |
| 24/03/2001 | Bridport | 2 | 1 | Westbury United |
| 24/03/2001 | Paulton Rovers | 6 | 0 | Minehead Town (-3) |
| 19/03/2001 | Taunton Town | 4 | 0 | Bristol Manor Farm |
| 17/03/2001 | Bideford | 3 | 0 | Backwell United |
| 17/03/2001 | Minehead Town (-3) | 2 | 3 | Welton Rovers (P) |
| 14/03/2001 | Westbury United | 0 | 2 | Yeovil Town Reserves |
| 13/03/2001 | Bideford | 2 | 0 | Elmore |
| 13/03/2001 | Bristol Manor Farm | 1 | 2 | Backwell United |
| 13/03/2001 | Devizes Town (P) | 0 | 1 | Paulton Rovers |
| 13/03/2001 | Welton Rovers (P) | 1 | 1 | Bishop Sutton |
| 11/03/2001 | Barnstaple Town | 2 | 0 | Odd Down |
| 10/03/2001 | Backwell United | 3 | 1 | Elmore |
| 10/03/2001 | Barnstaple Town | 2 | 6 | Devizes Town (P) |
| 10/03/2001 | Bridport | 1 | 7 | Taunton Town |
| 10/03/2001 | Chippenham Town | 0 | 1 | Bideford |
| 10/03/2001 | Odd Down | 0 | 0 | Yeovil Town Reserves |
| 06/03/2001 | Melksham Town | 2 | 1 | Bristol Manor Farm |
| 04/03/2001 | Dawlish Town | 3 | 1 | Westbury United |
| 03/03/2001 | Brislington | 4 | 0 | Barnstaple Town |
| 03/03/2001 | Bristol Manor Farm | 2 | 0 | Westbury United |
| 03/03/2001 | Dawlish Town | 2 | 0 | Welton Rovers (P) |
| 03/03/2001 | Devizes Town (P) | 6 | 0 | Yeovil Town Reserves |
| 03/03/2001 | Elmore | 3 | 3 | Paulton Rovers |
| 01/03/2001 | Odd Down | 3 | 1 | Backwell United |
| 27/02/2001 | Brislington | 2 | 0 | Westbury United |
| 27/02/2001 | Melksham Town | 2 | 1 | Welton Rovers (P) |
| 25/02/2001 | Elmore | 3 | 0 | Bristol Manor Farm |
| 24/02/2001 | Barnstaple Town | 1 | 2 | Chippenham Town |
| 24/02/2001 | Bideford | 6 | 1 | Bristol Manor Farm |
| 24/02/2001 | Bishop Sutton | 2 | 2 | Brislington |
| 24/02/2001 | Bridport | 0 | 3 | Melksham Town |
| 24/02/2001 | Minehead Town (-3) | 1 | 2 | Taunton Town |
| 24/02/2001 | Paulton Rovers | 1 | 1 | Odd Down |
| 24/02/2001 | Welton Rovers (P) | 1 | 1 | Devizes Town (P) |
| 24/02/2001 | Westbury United | 2 | 1 | Bridgwater Town (-3) |
| 24/02/2001 | Yeovil Town Reserves | 6 | 2 | Elmore |
| 20/02/2001 | Bideford | 2 | 0 | Dawlish Town |
| 20/02/2001 | Bridport | 5 | 1 | Barnstaple Town |
| 20/02/2001 | Devizes Town (P) | 2 | 3 | Chippenham Town |
| 20/02/2001 | Melksham Town | 0 | 1 | Backwell United |
| 17/02/2001 | Backwell United | 3 | 0 | Bridgwater Town (-3) |
| 17/02/2001 | Bishop Sutton | 1 | 1 | Barnstaple Town |
| 17/02/2001 | Brislington | 2 | 0 | Welton Rovers (P) |
| 17/02/2001 | Chippenham Town | 5 | 0 | Yeovil Town Reserves |
| 17/02/2001 | Dawlish Town | 1 | 5 | Paulton Rovers |
| 17/02/2001 | Devizes Town (P) | 4 | 3 | Bridport |
| 17/02/2001 | Elmore | 2 | 0 | Minehead Town (-3) |
| 17/02/2001 | Melksham Town | 1 | 2 | Bideford |
| 17/02/2001 | Odd Down | 2 | 1 | Bristol Manor Farm |
| 17/02/2001 | Taunton Town | 11 | 0 | Westbury United |
| 14/02/2001 | Welton Rovers (P) | 0 | 3 | Chippenham Town |
| 13/02/2001 | Devizes Town (P) | 3 | 0 | Bridgwater Town (-3) |
| 13/02/2001 | Odd Down | 1 | 2 | Brislington |
| 13/02/2001 | Taunton Town | 4 | 1 | Dawlish Town |
| 10/02/2001 | Barnstaple Town | 1 | 3 | Bridgwater Town (-3) |
| 10/02/2001 | Bideford | 2 | 0 | Odd Down |
| 10/02/2001 | Bridport | 1 | 1 | Devizes Town (P) |
| 10/02/2001 | Bristol Manor Farm | 0 | 0 | Welton Rovers (P) |
| 10/02/2001 | Paulton Rovers | 2 | 1 | Brislington |
| 10/02/2001 | Westbury United | 0 | 0 | Dawlish Town |
| 10/02/2001 | Yeovil Town Reserves | 0 | 0 | Backwell United |
| 03/02/2001 | Elmore | 0 | 4 | Brislington |
| 03/02/2001 | Melksham Town | 2 | 5 | Taunton Town |
| 03/02/2001 | Odd Down | 2 | 0 | Westbury United |
| 30/01/2001 | Backwell United | 0 | 1 | Taunton Town |
| 30/01/2001 | Melksham Town | 2 | 1 | Brislington |
| 28/01/2001 | Bridport | 1 | 1 | Chippenham Town |
| 27/01/2001 | Backwell United | 3 | 1 | Bishop Sutton |
| 27/01/2001 | Bristol Manor Farm | 1 | 1 | Melksham Town |
| 27/01/2001 | Paulton Rovers | 4 | 2 | Dawlish Town |
| 27/01/2001 | Taunton Town | 7 | 0 | Odd Down |
| 27/01/2001 | Welton Rovers (P) | 2 | 0 | Bideford |
| 23/01/2001 | Devizes Town (P) | 1 | 2 | Welton Rovers (P) |
| 20/01/2001 | Backwell United | 0 | 1 | Welton Rovers (P) |
| 20/01/2001 | Barnstaple Town | 0 | 2 | Yeovil Town Reserves |
| 20/01/2001 | Bishop Sutton | 2 | 2 | Bridport |
| 20/01/2001 | Brislington | 5 | 1 | Minehead Town (-3) |
| 20/01/2001 | Dawlish Town | 3 | 0 | Bristol Manor Farm |
| 20/01/2001 | Elmore | 2 | 2 | Odd Down |
| 16/01/2001 | Bridgwater Town (-3) | 0 | 1 | Barnstaple Town |
| 13/01/2001 | Bridport | 1 | 1 | Bridgwater Town (-3) |
| 13/01/2001 | Bristol Manor Farm | 0 | 3 | Brislington |
| 13/01/2001 | Devizes Town (P) | 0 | 3 | Bideford |
| 13/01/2001 | Minehead Town (-3) | 0 | 3 | Chippenham Town |
| 13/01/2001 | Taunton Town | 2 | 0 | Elmore |
| 13/01/2001 | Welton Rovers (P) | 7 | 0 | Barnstaple Town |
| 10/01/2001 | Chippenham Town | 2 | 1 | Backwell United |
| 10/01/2001 | Taunton Town | 4 | 0 | Barnstaple Town |
| 10/01/2001 | Welton Rovers (P) | 0 | 0 | Odd Down |
| 06/01/2001 | Backwell United | 0 | 0 | Bridport |
| 06/01/2001 | Barnstaple Town | 1 | 3 | Paulton Rovers |
| 06/01/2001 | Bishop Sutton | 2 | 1 | Minehead Town (-3) |
| 06/01/2001 | Bridgwater Town (-3) | 0 | 5 | Bideford |
| 06/01/2001 | Brislington | 0 | 0 | Bristol Manor Farm |
| 06/01/2001 | Chippenham Town | 5 | 3 | Taunton Town |
| 06/01/2001 | Dawlish Town | 4 | 2 | Odd Down |
| 06/01/2001 | Devizes Town (P) | 3 | 2 | Melksham Town |
| 06/01/2001 | Elmore | 4 | 1 | Westbury United |
| 30/12/2000 | Bideford | 4 | 1 | Brislington |
| 26/12/2000 | Barnstaple Town | 2 | 0 | Bideford |
| 26/12/2000 | Bridgwater Town (-3) | 2 | 4 | Taunton Town |
| 26/12/2000 | Bristol Manor Farm | 2 | 0 | Bishop Sutton |
| 26/12/2000 | Chippenham Town | 2 | 1 | Melksham Town |
| 26/12/2000 | Devizes Town (P) | 3 | 0 | Westbury United |
| 26/12/2000 | Elmore | 1 | 2 | Dawlish Town |
| 26/12/2000 | Minehead Town (-3) | 1 | 0 | Backwell United |
| 23/12/2000 | Backwell United | 1 | 2 | Paulton Rovers |
| 23/12/2000 | Barnstaple Town | 3 | 0 | Minehead Town (-3) |
| 23/12/2000 | Bishop Sutton | 1 | 1 | Bideford |
| 23/12/2000 | Bridgwater Town (-3) | 1 | 2 | Bristol Manor Farm |
| 23/12/2000 | Brislington | 1 | 1 | Taunton Town |
| 23/12/2000 | Dawlish Town | 0 | 1 | Melksham Town |
| 23/12/2000 | Elmore | 2 | 4 | Devizes Town (P) |
| 23/12/2000 | Welton Rovers (P) | 1 | 2 | Bridport |
| 23/12/2000 | Yeovil Town Reserves | 5 | 0 | Westbury United |
| 20/12/2000 | Bishop Sutton | 1 | 4 | Taunton Town |
| 19/12/2000 | Chippenham Town | 1 | 1 | Brislington |
| 16/12/2000 | Bideford | 1 | 0 | Bridgwater Town (-3) |
| 16/12/2000 | Melksham Town | 3 | 2 | Devizes Town (P) |
| 16/12/2000 | Odd Down | 4 | 1 | Minehead Town (-3) |
| 16/12/2000 | Paulton Rovers | 6 | 0 | Barnstaple Town |
| 16/12/2000 | Welton Rovers (P) | 2 | 2 | Yeovil Town Reserves |
| 09/12/2000 | Barnstaple Town | 1 | 0 | Bristol Manor Farm |
| 09/12/2000 | Brislington | 3 | 0 | Melksham Town |
| 09/12/2000 | Dawlish Town | 2 | 1 | Devizes Town (P) |
| 09/12/2000 | Elmore | 2 | 2 | Backwell United |
| 09/12/2000 | Welton Rovers (P) | 9 | 1 | Minehead Town (-3) |
| 09/12/2000 | Westbury United | 1 | 1 | Bridport |
| 02/12/2000 | Minehead Town (-3) | 0 | 4 | Bridgwater Town (-3) |
| 29/11/2000 | Barnstaple Town | 1 | 1 | Dawlish Town |
| 29/11/2000 | Chippenham Town | 2 | 0 | Welton Rovers (P) |
| 25/11/2000 | Bideford | 1 | 2 | Welton Rovers (P) |
| 25/11/2000 | Minehead Town (-3) | 0 | 3 | Yeovil Town Reserves |
| 18/11/2000 | Backwell United | 3 | 1 | Bideford |
| 18/11/2000 | Bridport | 6 | 0 | Minehead Town (-3) |
| 18/11/2000 | Brislington | 1 | 2 | Devizes Town (P) |
| 18/11/2000 | Welton Rovers (P) | 1 | 1 | Bristol Manor Farm |
| 14/11/2000 | Backwell United | 3 | 1 | Westbury United |
| 14/11/2000 | Bristol Manor Farm | 0 | 1 | Paulton Rovers |
| 11/11/2000 | Bideford | 2 | 1 | Bridport |
| 11/11/2000 | Dawlish Town | 3 | 1 | Minehead Town (-3) |
| 07/11/2000 | Bristol Manor Farm | 1 | 1 | Bridgwater Town (-3) |
| 04/11/2000 | Barnstaple Town | 0 | 1 | Elmore |
| 04/11/2000 | Bridport | 3 | 0 | Bristol Manor Farm |
| 01/11/2000 | Yeovil Town Reserves | 3 | 1 | Taunton Town |
| 31/10/2000 | Paulton Rovers | 0 | 0 | Backwell United |
| 28/10/2000 | Bideford | 3 | 0 | Minehead Town (-3) |
| 28/10/2000 | Chippenham Town | 1 | 0 | Bridgwater Town (-3) |
| 28/10/2000 | Dawlish Town | 4 | 1 | Bishop Sutton |
| 28/10/2000 | Taunton Town | 1 | 2 | Bridport |
| 21/10/2000 | Backwell United | 1 | 2 | Devizes Town (P) |
| 21/10/2000 | Bishop Sutton | 1 | 5 | Chippenham Town |
| 21/10/2000 | Bridport | 1 | 0 | Odd Down |
| 21/10/2000 | Minehead Town (-3) | 1 | 3 | Bristol Manor Farm |
| 21/10/2000 | Paulton Rovers | 2 | 3 | Taunton Town |
| 21/10/2000 | Westbury United | 1 | 2 | Welton Rovers (P) |
| 17/10/2000 | Bideford | 0 | 1 | Yeovil Town Reserves |
| 17/10/2000 | Bridport | 0 | 2 | Dawlish Town |
| 17/10/2000 | Devizes Town (P) | 2 | 1 | Brislington |
| 17/10/2000 | Elmore | 1 | 2 | Bridgwater Town (-3) |
| 17/10/2000 | Minehead Town (-3) | 2 | 3 | Barnstaple Town |
| 17/10/2000 | Odd Down | 0 | 1 | Chippenham Town |
| 17/10/2000 | Paulton Rovers | 2 | 0 | Westbury United |
| 14/10/2000 | Bridgwater Town (-3) | 0 | 0 | Westbury United |
| 14/10/2000 | Brislington | 2 | 1 | Bishop Sutton |
| 14/10/2000 | Bristol Manor Farm | 1 | 3 | Bideford |
| 14/10/2000 | Chippenham Town | 0 | 1 | Barnstaple Town |
| 14/10/2000 | Dawlish Town | 0 | 4 | Backwell United |
| 14/10/2000 | Elmore | 2 | 1 | Yeovil Town Reserves |
| 14/10/2000 | Melksham Town | 1 | 1 | Bridport |
| 14/10/2000 | Odd Down | 2 | 4 | Paulton Rovers |
| 14/10/2000 | Taunton Town | 8 | 1 | Minehead Town (-3) |
| 10/10/2000 | Melksham Town | 3 | 2 | Bishop Sutton |
| 07/10/2000 | Backwell United | 1 | 2 | Chippenham Town |
| 07/10/2000 | Barnstaple Town | 3 | 3 | Brislington |
| 07/10/2000 | Bideford | 0 | 5 | Taunton Town |
| 07/10/2000 | Bishop Sutton | 2 | 2 | Bridgwater Town (-3) |
| 07/10/2000 | Bridport | 0 | 2 | Elmore |
| 07/10/2000 | Minehead Town (-3) | 2 | 1 | Odd Down |
| 07/10/2000 | Paulton Rovers | 3 | 1 | Melksham Town |
| 07/10/2000 | Welton Rovers (P) | 0 | 1 | Dawlish Town |
| 07/10/2000 | Westbury United | 1 | 3 | Bristol Manor Farm |
| 07/10/2000 | Yeovil Town Reserves | 4 | 0 | Devizes Town (P) |
| 04/10/2000 | Bishop Sutton | 1 | 1 | Backwell United |
| 04/10/2000 | Taunton Town | 5 | 1 | Brislington |
| 30/09/2000 | Bridport | 3 | 4 | Welton Rovers (P) |
| 30/09/2000 | Brislington | 0 | 1 | Backwell United |
| 30/09/2000 | Dawlish Town | 0 | 3 | Yeovil Town Reserves |
| 30/09/2000 | Elmore | 2 | 4 | Barnstaple Town |
| 30/09/2000 | Minehead Town (-3) | 0 | 3 | Melksham Town |
| 30/09/2000 | Odd Down | 1 | 2 | Bideford |
| 27/09/2000 | Welton Rovers (P) | 1 | 1 | Brislington |
| 26/09/2000 | Backwell United | 1 | 0 | Bristol Manor Farm |
| 23/09/2000 | Chippenham Town | 2 | 0 | Odd Down |
| 19/09/2000 | Bristol Manor Farm | 0 | 0 | Odd Down |
| 19/09/2000 | Minehead Town (-3) | 0 | 8 | Elmore |
| 19/09/2000 | Paulton Rovers | 1 | 4 | Devizes Town (P) |
| 19/09/2000 | Westbury United | 2 | 5 | Taunton Town |
| 16/09/2000 | Odd Down | 0 | 4 | Taunton Town |
| 16/09/2000 | Yeovil Town Reserves | 0 | 1 | Bridport |
| 09/09/2000 | Barnstaple Town | 0 | 1 | Welton Rovers (P) |
| 09/09/2000 | Bideford | 3 | 2 | Bishop Sutton |
| 09/09/2000 | Bridgwater Town (-3) | 1 | 1 | Yeovil Town Reserves |
| 09/09/2000 | Bristol Manor Farm | 1 | 2 | Elmore |
| 09/09/2000 | Chippenham Town | 0 | 2 | Paulton Rovers |
| 09/09/2000 | Minehead Town (-3) | 4 | 2 | Dawlish Town |
| 09/09/2000 | Taunton Town | 3 | 2 | Melksham Town |
| 05/09/2000 | Westbury United | 0 | 1 | Odd Down |
| 02/09/2000 | Dawlish Town | 1 | 1 | Bridport |
| 30/08/2000 | Bishop Sutton | 1 | 3 | Yeovil Town Reserves |
| 30/08/2000 | Dawlish Town | 2 | 1 | Bideford |
| 29/08/2000 | Bridgwater Town (-3) | 1 | 0 | Bridport |
| 29/08/2000 | Brislington | 1 | 1 | Paulton Rovers |
| 29/08/2000 | Devizes Town (P) | 2 | 0 | Bristol Manor Farm |
| 29/08/2000 | Elmore | 1 | 6 | Taunton Town |
| 29/08/2000 | Melksham Town | 2 | 0 | Odd Down |
| 26/08/2000 | Bideford | 2 | 2 | Chippenham Town |
| 26/08/2000 | Bristol Manor Farm | 2 | 0 | Dawlish Town |
| 26/08/2000 | Odd Down | 1 | 0 | Elmore |
| 26/08/2000 | Paulton Rovers | 2 | 0 | Bridgwater Town (-3) |
| 26/08/2000 | Welton Rovers (P) | 2 | 0 | Backwell United |
| 26/08/2000 | Westbury United | 4 | 1 | Minehead Town (-3) |
| 26/08/2000 | Yeovil Town Reserves | 3 | 2 | Barnstaple Town |
| 23/08/2000 | Barnstaple Town | 1 | 4 | Taunton Town |
| 23/08/2000 | Yeovil Town Reserves | 0 | 0 | Chippenham Town |
| 22/08/2000 | Bridport | 1 | 1 | Bishop Sutton |
| 22/08/2000 | Minehead Town (-3) | 3 | 1 | Brislington |
| 22/08/2000 | Westbury United | 0 | 1 | Melksham Town |
| 19/08/2000 | Backwell United | 3 | 2 | Yeovil Town Reserves |
| 19/08/2000 | Barnstaple Town | 1 | 1 | Bridport |
| 19/08/2000 | Bishop Sutton | 2 | 2 | Paulton Rovers |
| 19/08/2000 | Bridgwater Town (-3) | 5 | 3 | Minehead Town (-3) |
| 19/08/2000 | Brislington | 0 | 0 | Bideford |
| 19/08/2000 | Chippenham Town | 3 | 1 | Bristol Manor Farm |
| 19/08/2000 | Dawlish Town | 2 | 4 | Taunton Town |
| 19/08/2000 | Devizes Town (P) | 1 | 0 | Odd Down |
| 19/08/2000 | Elmore | 2 | 4 | Melksham Town |
| 19/08/2000 | Welton Rovers (P) | 1 | 0 | Westbury United |
| 16/08/2000 | Bishop Sutton | 4 | 2 | Odd Down |
| 16/08/2000 | Taunton Town | 4 | 1 | Devizes Town (P) |
| 16/08/2000 | Yeovil Town Reserves | 9 | 1 | Minehead Town (-3) |
| 15/08/2000 | Bridgwater Town (-3) | 2 | 1 | Melksham Town |
| 12/08/2000 | Bideford | 1 | 1 | Westbury United |
| 12/08/2000 | Bridgwater Town (-3) | 4 | 2 | Brislington |
| 12/08/2000 | Bristol Manor Farm | 4 | 1 | Minehead Town (-3) |
| 12/08/2000 | Chippenham Town | 4 | 0 | Bishop Sutton |
| 12/08/2000 | Dawlish Town | 1 | 4 | Barnstaple Town |
| 12/08/2000 | Devizes Town (P) | 1 | 4 | Backwell United |
| 12/08/2000 | Elmore | 2 | 0 | Welton Rovers (P) |
| 12/08/2000 | Melksham Town | 1 | 2 | Yeovil Town Reserves |
| 12/08/2000 | Odd Down | 2 | 0 | Bridport |
| 12/08/2000 | Taunton Town | 2 | 2 | Paulton Rovers |